VTA1 Protein (AA 1-307) (His tag)

N° du produit ABIN667681

Détail du produit

Antigène: VTA1 (Vps20-Associated 1 Homolog (VTA1))

Type de proteíne: Recombinant

Attributs du protein: AA 1-307

Origine: Humain

Source: Escherichia coli (E. coli)

Purification/Conjugué: Cette VTA1 protéine est marqué à la His tag.

Application: SDS-PAGE (SDS)

Attributs du produit: VTA1, 1-307aa , Human, His tag, E.coli

Pureté: > 95 % by SDS - PAGE

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1mg/ml (determined by Bradford assay)

Buffer: Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 2mM DTT, 10% glycerol, 200mM NaCl

Stock: 4 °C

Détail du antigène

Antigène: VTA1 (Vps20-Associated 1 Homolog (VTA1))

Autre désignation: VTA1 (VTA1 Produits)

Synonymes: C6orf55 Protein, DRG-1 Protein, DRG1 Protein, LIP5 Protein, My012 Protein, SBP1 Protein, 1110001D18Rik Protein, 1110059P08Rik Protein, AU040813 Protein, C85340 Protein, Lip5 Protein, RGD1305031 Protein, Vps20-associated 1 homolog Protein, vesicle trafficking 1 Protein, vesicle (multivesicular body) trafficking 1 Protein, Vta1 Protein, VTA1 Protein

Sujet: VTA1 (Vps20-associated 1 homolog), also known as LIP5 (LYST-interacting protein 5), DRG1 (Dopamine-responsive protein DRG-1), SBP1 (SKD1 bindingprotein 1), belongs to the VTA1 family. This protein Involved in the endosomal multivesicular bodies (MVB) pathway. MVBs contain intraluminal vesicles (ILVs) that are generated by invagination and scission from the limiting membrane of the endosome and mostly are delivered to lysosomes enabling degradation of membrane proteins, such as stimulated growth factor receptors, lysosomal enzymes and lipids. Also, VTA1 is known to interact with CHMP1B, CHMP2A, CHMP5, VPS4B, KIAA0174 (IST1) and possibly CHMP3. Recombinant human VTA1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: vacuolar protein sorting-associated protein VTA1 homolog, DRG-1, DRG1, LIP5, SBP1. NCBI no.: NP_057569

Poids moléculaire: 36.5kDa (331aa), confirmed by MALDI-TOF