Grancalcin Protein (AA 1-217) (His tag)

N° du produit ABIN7279305

Détail du produit

Antigène: Grancalcin (GCA) (Grancalcin, EF-Hand Calcium Binding Protein (GCA))

Type de proteíne: Recombinant

Attributs du protein: AA 1-217

Origine: Humain

Source: Escherichia coli (E. coli)

Purification/Conjugué: Cette Grancalcin protéine est marqué à la His tag.

Application: SDS-PAGE (SDS)

Attributs du produit: GCA, 1-217aa, Human, His tag, E.coli

Pureté: > 95 % by SDS - PAGE

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1.0 mg/ml (determined by BCA assay)

Buffer: Liquid. 20mM Tris-HCl buffer (pH8.0) containing 20% glycerol 0.1M NaCl

Stock: 4 °C

Détail du antigène

Antigène: Grancalcin (GCA) (Grancalcin, EF-Hand Calcium Binding Protein (GCA))

Autre désignation: GCA (GCA Produits)

Synonymes: Grancalcin Protein, 5133401E04Rik Protein, AI573844 Protein, GCL Protein, zgc:92027 Protein, grancalcin Protein, Grancalcin Protein, zgc:92027 Protein, GCA Protein, gran Protein, LOC100280890 Protein, Gca Protein

Sujet: GCA, also known as Grancalcin, is calcium-binding protein that is especially abundant in human neutrophils. It belongs to the penta EF-hand (PEF) subfamily of EF-hand proteins, which also comprises calpain, sorcin, peflin, and ALG-2. This protein undergoes important conformational changes upon binding of calcium, which subsequently exposes hydrophobic amino acid residues, which direct the protein to hydrophobic surfaces. It interacts with L-plastin, a protein known to have actin bundling activity, which suggests that GCA may play a role in the regulation of neutrophils adhesion. Recombinant human GCA protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography. Synonyms: Grancalcin, GCL. NCBI no.: NP_036330

Poids moléculaire: 26.1 kDa (237aa), confirmed by MALDI-TOF