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DUSP10 Protein (AA 149-482) (His tag)

DUSP10 Origine: Humain Hôte: Escherichia coli (E. coli) Recombinant > 90 % by SDS - PAGE SDS
N° du produit ABIN668018
  • Antigène Voir toutes DUSP10 Protéines
    DUSP10 (Dual Specificity Phosphatase 10 (DUSP10))
    Type de proteíne
    Recombinant
    Attributs du protein
    AA 149-482
    Origine
    • 3
    • 1
    • 1
    Humain
    Source
    • 2
    • 1
    • 1
    • 1
    Escherichia coli (E. coli)
    Purification/Conjugué
    Cette DUSP10 protéine est marqué à la His tag.
    Application
    SDS-PAGE (SDS)
    Attributs du produit
    DUSP10, 149-482aa, Human, His tag, E.coli
    Pureté
    > 90 % by SDS - PAGE
    Top Product
    Discover our top product DUSP10 Protéine
  • Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.25mg/ml (determined by Bradford assay)
    Buffer
    Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 2mM DTT, 50% glycerol, 200mM NaCl
    Stock
    4 °C
  • Antigène
    DUSP10 (Dual Specificity Phosphatase 10 (DUSP10))
    Autre désignation
    DUSP10 (DUSP10 Produits)
    Synonymes
    DUSP10 Protein, MKP-5 Protein, MKP5 Protein, 2610306G15Rik Protein, AI158871 Protein, Mkp-5 Protein, Mkp5 Protein, dual specificity phosphatase 10 Protein, DUSP10 Protein, Dusp10 Protein
    Sujet
    DUSP10 (Dual specificity protein phosphatase 10) belongs to the protein-tyrosine phosphatase family. Dual specificity protein phosphatases(DUSPs) inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the MAPK superfamily (MAPK/ERK, SAPK/JNK, p38), which is associated with cellular proliferation and differentiation. DUSP10 has been shown to interact with MAPK14 and MAPK8. When expressed in mammalian cells, DUSP10 blocks the enzymatic activation of MAP kinases with the selectivity p38 approximately JNK/SAPK >> ERK. Recombinant human DUSP10 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: Dual specificity protein phosphatase 10, MKP-5, MKP5. NCBI no.: NP_009138
    Poids moléculaire
    40.4kDa (359aa), confirmed by MALDI-TOF
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