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GMP Synthase Protein (AA 1-693) (His tag)

GMPS Origine: Humain Hôte: Escherichia coli (E. coli) Recombinant > 90 % by SDS - PAGE SDS
N° du produit ABIN668022
  • Antigène Voir toutes GMP Synthase (GMPS) Protéines
    GMP Synthase (GMPS) (Guanine Monophosphate Synthetase (GMPS))
    Type de proteíne
    Recombinant
    Attributs du protein
    AA 1-693
    Origine
    • 5
    • 1
    • 1
    Humain
    Source
    • 2
    • 2
    • 1
    • 1
    • 1
    Escherichia coli (E. coli)
    Purification/Conjugué
    Cette GMP Synthase protéine est marqué à la His tag.
    Application
    SDS-PAGE (SDS)
    Attributs du produit
    GMPS, 1-693aa , Human, His tag, E.coli
    Pureté
    > 90 % by SDS - PAGE
    Top Product
    Discover our top product GMPS Protéine
  • Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.5 mg/ml (determined by Bradford assay)
    Buffer
    Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 1mM DTT, 30% glycerol, 0.1M NaCl
    Stock
    4 °C
  • Antigène
    GMP Synthase (GMPS) (Guanine Monophosphate Synthetase (GMPS))
    Autre désignation
    GMPS (GMPS Produits)
    Synonymes
    GMPS Protein, AA591640 Protein, AI047208 Protein, sb:cb632 Protein, wu:fb76b01 Protein, wu:fi05a09 Protein, zgc:66002 Protein, guanine monophosphate synthase Protein, guanine monophosphate synthase L homeolog Protein, guanine monophosphate synthetase Protein, GMPS Protein, gmps.L Protein, gmps Protein, Gmps Protein
    Sujet
    GMP synthase, also known as GMPS, is involved in purine biosynthesis. Existing as a homodimer, GMPS catalyzes the last step in the GMP synthesis pathway, namely the ATP-dependent amination of XMP to GMP. GMPS contains one GMP-binding domain and one glutamine amidotransferase type-1 domain through which it conveys its catalytic activity. Chromosomal translocations involving the gene encoding GMPS are associated with acute myeloid leukemias, suggesting a possible role for GMPS in carcinogenesis. Recombinant human GMPS protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: GMP synthase [glutamine-hydrolyzing], Glutamine amidotransferase, guanine monophosphate synthetase. NCBI no.: NP_003866
    Poids moléculaire
    79.2 kDa (717aa)
    Pathways
    Ribonucleoside Biosynthetic Process
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