Thrombospondin 2 Protein (THBS2) (AA 19-1172) (His tag)

N° du produit ABIN6809949

Détail du produit

Antigène: Thrombospondin 2 (THBS2)

Type de proteíne: Recombinant

Attributs du protein: AA 19-1172

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette Thrombospondin 2 protéine est marqué à la His tag.

Pureté: >90 % as determined by SDS-PAGE.

niveau d'endotoxine: Less than 1.0 EU per μg by the LAL method.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: PBS, pH 7.4

Stock: -20 °C

Détail du antigène

Antigène: Thrombospondin 2 (THBS2)

Autre désignation: Thrombospondin-2 (THBS2 Produits)

Synonymes: THBS1 Protein, tsp2 Protein, thbs2 Protein, TSP2 Protein, TMEM200A Protein, TSP-2 Protein, Thbs-2 Protein, thrombospondin 2 Protein, thrombospondin 2 L homeolog Protein, thrombospondin 2a Protein, THBS2 Protein, thbs2.L Protein, thbs2a Protein, Thbs2 Protein

Sujet: Thrombospondin-2 is also known as THBS2, TSP2, TSP-2. Thrombospondin-2 (TSP2) is an anti-angiogenic matricellular protein that inhibits tumor growth and angiogenesis. Adhesive glycoprotein that mediates cell-to-cell and cell-to-matrix interactions. Ligand for CD36 mediating antiangiogenic properties. 2 SNPs in the intron region of THBS2 gene (rs6422747 and rs6422748) were associated with susceptibility of IDD. However, they were not related with severity of IDD, including the total number of degenerative disc and level of IDD. Thrombospondin 2, an important regulator of synaptogenesis in central nervous system development, was distributed in retinal macroglia cells, and its receptor α2δ-1 was in retinal neurons. activated macroglia cells may participate in alterations of presynaptic proteins of retinal neurons following elevated hydrostatic pressure, and macroglia-derived thrombospondin 2 may modulate these changes via binding to its neuronal receptor α2δ-1.

Poids moléculaire: 129.7 kDa

NCBI Accession: NP_003238