TNFSF14 Protein (AA 74-240) (His tag)
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- Antigène Voir toutes TNFSF14 Protéines
- TNFSF14 (Tumor Necrosis Factor (Ligand) Superfamily, Member 14 (TNFSF14))
- Type de proteíne
- Recombinant
- Activité biologique
- Active
- Attributs du protein
- AA 74-240
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Origine
- Humain
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Source
- HEK-293 Cells
- Purification/Conjugué
- Cette TNFSF14 protéine est marqué à la His tag.
- Pureté
- >90 % as determined by SDS-PAGE.
- niveau d'endotoxine
- Less than 1.0 EU per μg by the LAL method.
- Top Product
- Discover our top product TNFSF14 Protéine
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- PBS, pH 7.4
- Stock
- -20 °C
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- Antigène
- TNFSF14 (Tumor Necrosis Factor (Ligand) Superfamily, Member 14 (TNFSF14))
- Autre désignation
- LIGHT (TNFSF14 Produits)
- Synonymes
- TNFSF14 Protein, CD258 Protein, HVEML Protein, LIGHT Protein, LTg Protein, TR2 Protein, HVEM-L Protein, Ly113 Protein, TNF superfamily member 14 Protein, tumor necrosis factor (ligand) superfamily, member 14 Protein, TNFSF14 Protein, Tnfsf14 Protein
- Sujet
- Tumor necrosis factor ligand superfamily member 14(LIGHT) is a tumor necrosis factor (TNF) superfamily ligand that regulates T cell immune responses by signaling through the herpes virus entry mediator (HVEM) and the lymphotoxin beta receptor (LTbetaR). LIGHT has emerged as a potent initiator of T cell co-stimulation signals effecting CTL-mediated tumor rejection, allograft rejection and graft versus host disease. Constitutive expression of LIGHT leads to tissue destruction and autoimmune-like disease syndromes.
- Poids moléculaire
- 58.3 kDa
- Pathways
- Cancer Immune Checkpoints
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