SARS-Coronavirus Nonstructural Protein 8 (SARS-CoV NSP8) protein (His tag)

N° du produit ABIN6952706

Détail du produit

Antigène: SARS-Coronavirus Nonstructural Protein 8 (SARS-CoV NSP8)

Type de proteíne: Recombinant

Origine: SARS Coronavirus-2 (SARS-CoV-2)

Source: Escherichia coli (E. coli)

Purification/Conjugué: His tag

Application: SDS-PAGE (SDS)

Fonction: SARS-CoV-2 (COVID-19) NSP8 Protein, His Tag

Séquence: AA 1-198

Attributs du produit: SARS-CoV-2 NSP8, His Tag (NS8-C5149) is expressed from E.coli cells. It contains AA Ala 1 - Gln 198 (Accession # YP_009725304.1).Predicted N-terminus: Met
This protein carries a polyhistidine tag at the N-terminus.

Pureté: >95 % as determined by SDS-PAGE.

Stérilité: 0.2 μm filtered

niveau d'endotoxine: Less than 1.0 EU per μg by the LAL method.

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: 20 mM Tris, 250 mM NaCl, pH 8.5

Conseil sur la manipulation: Please avoid repeated freeze-thaw cycles.

Stock: -80 °C

Stockage commentaire: The product MUST be stored at -70°C or lower upon receipt
-70°C for 3 months under sterile conditions.

Détail du antigène

Antigène: SARS-Coronavirus Nonstructural Protein 8 (SARS-CoV NSP8)

Autre désignation: NSP8 (SARS-CoV NSP8 Produits)

Synonymes: pp1a Protein, pp1ab Protein, orf1ab polyprotein (pp1ab) Protein, orf1ab Protein

Classe de substances: Viral Protein

Sujet: NSP8, forms a hexadecamer with nsp7 (8 subunits of each) that may participate in viral replication by acting as a primase. Alternatively, may synthesize substantially longer products than oligonucleotide primers. To ultimately combat the emerging COVID-19 pandemic, it is desired to develop an effective and safe vaccine against this highly contagious disease caused by the SARS-CoV-2 coronavirus. By investigating the entire proteome of SARS-CoV-2, six proteins, including the S protein and five non-structural proteins (nsp3, 3CL-pro, and nsp8-10) were predicted to be adhesins, which are crucial to the viral adhering and host invasion. The S, nsp3, and nsp8 proteins were also predicted by Vaxign-ML to induce high protective antigenicity.

Poids moléculaire: 23.9 kDa

NCBI Accession: YP_009725304