CD51 Protein (Fc Tag)

N° du produit ABIN6964181

Détail du produit

Antigène: CD51 (ITGAV) (Integrin alpha V (ITGAV))

Type de proteíne: Recombinant

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette CD51 protéine est marqué à la Fc Tag.

Séquence: ITGAV(Phe31-Val992)+ ITGB1(Gln21-Asp728)+hFc(Glu99-Ala330)

Attributs du produit: Tagged Protein: C-Human Fc tag

Purification: affinity purification

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Reconstitute with deionized water

Buffer: Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.

Agent conservateur: Without preservative

Stock: -80 °C

Stockage commentaire: Store at -80°C for 12 months (Avoid repeated freezing and thawing)

Date de péremption: 12 months

Détail du antigène

Antigène: CD51 (ITGAV) (Integrin alpha V (ITGAV))

Autre désignation: ITGAV (ITGAV Produits)

Synonymes: 1110004F14Rik Protein, 2610028E01Rik Protein, CD51 Protein, D430040G12Rik Protein, MSK8 Protein, VNRA Protein, VTNR Protein, Cd51 Protein, integrin subunit alpha V Protein, integrin alpha V Protein, ITGAV Protein, Itgav Protein

Sujet: Synonymes: CD51, MSK8, VNRA, VTNR
Description: The product of this gene belongs to the integrin alpha chain family. Integrins are heterodimeric integral membrane proteins composed of an alpha subunit and a beta subunit that function in cell surface adhesion and signaling. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha V subunit. This subunit associates with beta 1, beta 3, beta 5, beta 6 and beta 8 subunits. The heterodimer consisting of alpha V and beta 3 subunits is also known as the vitronectin receptor. This integrin may regulate angiogenesis and cancer progression. Alternative splicing results in multiple transcript variants. Note that the integrin alpha 5 and integrin alpha V subunits are encoded by distinct genes.

Poids moléculaire: 131.34 kDa

UniProt: P06756

Pathways: Cell-Cell Junction Organization, Signaling Events mediated by VEGFR1 and VEGFR2, Growth Factor Binding, Integrin Complex