GNRHR Protein (Fc Tag)

N° du produit ABIN6964191

Détail du produit

Antigène: GNRHR (Gonadotropin-Releasing Hormone Receptor (GNRHR))

Type de proteíne: Recombinant

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette GNRHR protéine est marqué à la Fc Tag.

Fonction: Recombinant Human GNRHR Protein with C-terminal human Fc tag

Specificité: GNRHR (Met1-Arg38) hFc (Glu99-Ala330)

Attributs du produit: Extracellular Domain Protein

Purification: affinity purification

Pureté: The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Reconstitute with deionized water

Buffer: Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.

Agent conservateur: Without preservative

Stock: -20 °C,-80 °C

Stockage commentaire: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Date de péremption: 12 months

Détail du antigène

Antigène: GNRHR (Gonadotropin-Releasing Hormone Receptor (GNRHR))

Autre désignation: GNRHR (GNRHR Produits)

Synonymes: GNRHR1 Protein, GRHR Protein, HH7 Protein, LHRHR Protein, LRHR Protein, GNRHR Protein, GH1 Protein, Lhrhr Protein, GNRHR1/III Protein, GNRHR2 Protein, xgnrhr Protein, gnrhr3/ii Protein, gnrh-r Protein, gonadotropin releasing hormone receptor Protein, gonadotropin-releasing hormone receptor Protein, GNRHR Protein, Gnrhr Protein, gnrhr Protein, gnrh-r Protein

Sujet: Synonymes: GNRHR1, GRHR, HH7, LHRHR, LRHR
Description: This gene encodes the receptor for type 1 gonadotropin-releasing hormone. This receptor is a member of the seven-transmembrane, G-protein coupled receptor (GPCR) family. It is expressed on the surface of pituitary gonadotrope cells as well as lymphocytes, breast, ovary, and prostate. Following binding of gonadotropin-releasing hormone, the receptor associates with G-proteins that activate a phosphatidylinositol-calcium second messenger system. Activation of the receptor ultimately causes the release of gonadotropic luteinizing hormone (LH) and follicle stimulating hormone (FSH). Defects in this gene are a cause of hypogonadotropic hypogonadism (HH). Alternative splicing results in multiple transcript variants encoding different isoforms. More than 18 transcription initiation sites in the 5' region and multiple polyA signals in the 3' region have been identified for this gene.

Poids moléculaire: predicted molecular mass of 30.2 kDa after removal of the signal peptide.The apparent molecular mass of GNRHR-hFc is 35-55 kDa due to glycosylation.

UniProt: P30968