CCR1 Protein (Fc Tag)

N° du produit ABIN6964237

Détail du produit

Antigène: CCR1 (Chemokine (C-C Motif) Receptor 1 (CCR1))

Type de proteíne: Recombinant

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette CCR1 protéine est marqué à la Fc Tag.

Fonction: Recombinant human CCR1 protein with C-terminal human Fc tag

Specificité: CCR1 (Met1-Ala34) hFc (Glu99-Ala330)

Attributs du produit: Extracellular Domain Protein

Purification: affinity purification

Pureté: The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Reconstitute with deionized water

Buffer: Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.

Agent conservateur: Without preservative

Stock: -20 °C,-80 °C

Stockage commentaire: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Date de péremption: 12 months

Détail du antigène

Antigène: CCR1 (Chemokine (C-C Motif) Receptor 1 (CCR1))

Autre désignation: CCR1 (CCR1 Produits)

Synonymes: CD191 Protein, CKR-1 Protein, CKR1 Protein, CMKBR1 Protein, HM145 Protein, MIP1aR Protein, SCYAR1 Protein, Cmkbr1 Protein, Mip-1a-R Protein, C-C motif chemokine receptor 1 Protein, chemokine (C-C motif) receptor 1 Protein, CCR1 Protein, Ccr1 Protein

Sujet: Synonymes: CD191, CKR-1, CKR1, CMKBR1, HM145, MIP1aR, SCYAR1
Description: This gene encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. The ligands of this receptor include macrophage inflammatory protein 1 alpha (MIP-1 alpha), regulated on activation normal T expressed and secreted protein (RANTES), monocyte chemoattractant protein 3 (MCP-3), and myeloid progenitor inhibitory factor-1 (MPIF-1). Chemokines and their receptors mediated signal transduction are critical for the recruitment of effector immune cells to the site of inflammation. Knockout studies of the mouse homolog suggested the roles of this gene in host protection from inflammatory response, and susceptibility to virus and parasite. This gene and other chemokine receptor genes, including CCR2, CCRL2, CCR3, CCR5 and CCXCR1, are found to form a gene cluster on chromosome 3p. [provided by RefSeq, Jul 2008]

Poids moléculaire: predicted molecular mass of 30.0 kDa after removal of the signal peptide. The apparent molecular mass of CCR1-hFc is 35-55 kDa due to glycosylation.

UniProt: P32246