PSCA Protein (AA 12-86) (His tag,AVI tag,Biotin)

N° du produit ABIN6973200

Détail du produit

Antigène: PSCA (Prostate Stem Cell Antigen (PSCA))

Type de proteíne: Recombinant

Attributs du protein: AA 12-86

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette PSCA protéine est marqué à la His tag,AVI tag,Biotin.

Specificité: Biotinylation of this product is performed using Avitag™ technology. Briefly, the single lysine residue in the Avitag is enzymatically labeled with biotin.

Attributs du produit: Biotinylated Human PSCA Protein, His,Avitag™ (MALS verified)

Pureté: >90 % as determined by SDS-PAGE.

niveau d'endotoxine: Less than 1.0 EU per μg by the LAL method.

Information d'application

Indications d'application: MALS verified

Commentaires:

Ready-to-use Avitag™ biotinylated protein:
The product is exclusively produced using the Avitag™ technology. Briefly, a unique 15 amino acid peptide, the Avi tag, is introduced into the recombinant protein during expression vector construction. The single lysine residue in the Avi tag is enzymatically biotinylated by the E. Coli biotin ligase BirA.

This single-point enzymatic labeling technique brings many advantages for commonly used binding assays. The biotinylation happens on the lysine residue of Avi tag, and therefore does NOT interfere with the target protein's natural binding activities. In addition, when immobilized on an avidin-coated surface, the protein orientation is uniform because the position of the Avi tag in the protein is precisely controlled.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: PBS, pH 7.4

Stock: -20 °C

Détail du antigène

Antigène: PSCA (Prostate Stem Cell Antigen (PSCA))

Autre désignation: PSCA (PSCA Produits)

Synonymes: PRO232 Protein, 2210408B04Rik Protein, PSCA Protein, prostate stem cell antigen Protein, PSCA Protein, Psca Protein, LOC482068 Protein

Sujet: The Prostate stem cell antigen (PSCA) is a glycosylphosphatidylinositol (GPI)-anchored protein, plays an important role in tumorigenesis. The prostate stem cell antigen (PSCA) gene, which encodes a prostate-specific antigen (PSA), was identified as a gene involved in cell adhesion and proliferation. PSCA may be involved in the regulation of cell proliferation. Has a cell-proliferation inhibition activity in vitro. May act as a modulator of nicotinic acetylcholine receptors (nAChRs) activity. In vitro inhibits nicotine-induced signaling probably implicating alpha-3:beta-2- or alpha-7-containing nAChRs.

Poids moléculaire: 12.1 kDa