Secretory Component Protein (AA 19-603) (Twin-Strep tag)

N° du produit ABIN7013229

Détail du produit

Antigène: Secretory Component

Type de proteíne: Recombinant

Attributs du protein: AA 19-603

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette Secretory Component protéine est marqué à la Twin-Strep tag.

Fonction: Human Secretory Component, Twin Strep Tag

Pureté: >90 % as determined by SDS-PAGE.

niveau d'endotoxine: Less than 1.0 EU per μg by the LAL method.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: PBS, pH 7.3

Stock: -20 °C

Détail du antigène

Antigène: Secretory Component

Abstract: Secretory Component Produits

Synonymes: RNPIGR2 Protein, pIgA-R Protein, polymeric immunoglobulin receptor Protein, PIGR Protein, Pigr Protein

Sujet: The secretory component (SC) is a unique polypeptide chain that may be found in immunoglobulins A and M (IgA and IgM). The SC wraps around two IgA units joined by a J chain protein fragment, resulting in a configuration with each of the two antigen binding regions of the two constituent y-shaped antibodies exposed. One identified function of secretory components is to protect IgA antibodies from degradation by the gastric acids and enzymes of the digestive system. It also appears that SC may serve in the three-dimensional organization or in the transport and distribution of the resulting IgA complexes.

Poids moléculaire: 67.6 kDa

NCBI Accession: NP_002635