ACE2 Protein (AA 18-740) (mFc Tag)
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- Antigène Voir toutes ACE2 Protéines
- ACE2 (Angiotensin I Converting Enzyme 2 (ACE2))
- Type de proteíne
- Recombinant
- Activité biologique
- Active
- Attributs du protein
- AA 18-740
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Origine
- Humain
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Source
- HEK-293 Cells
- Purification/Conjugué
- Cette ACE2 protéine est marqué à la mFc Tag.
- Attributs du produit
- Human ACE2 / ACEH Protein, Mouse IgG1 Fc Tag (MALS verified)
- Pureté
- >95 % as determined by SDS-PAGE.
- niveau d'endotoxine
- Less than 1.0 EU per μg by the LAL method.
- Top Product
- Discover our top product ACE2 Protéine
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- Indications d'application
- MALS verified
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- 50 mM Tris, 150 mM NaCl, Arginine, pH 7.5
- Stock
- -80 °C
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- Antigène
- ACE2 (Angiotensin I Converting Enzyme 2 (ACE2))
- Autre désignation
- ACE2 (ACE2 Produits)
- Synonymes
- ACE1 Protein, CD143 Protein, DCP Protein, DCP1 Protein, ICH Protein, MVCD3 Protein, ACEH Protein, 2010305L05Rik Protein, zgc:92514 Protein, angiotensin I converting enzyme Protein, angiotensin I converting enzyme 2 Protein, angiotensin I converting enzyme (peptidyl-dipeptidase A) 2 Protein, ACE Protein, ACE2 Protein, Ace2 Protein, ace2 Protein
- Sujet
- Angiotensin-converting enzyme 2 (ACE2) is also known as ACEH (ACE homolog), is an integral membrane protein with considerable homologous to ACE, which belongs to the peptidase M2 family. ACE2 is an exopeptidase that catalyses the conversion of angiotensin I to the nonapeptide angiotensin, or the conversion of angiotensin II to angiotensin 1-7. ACE2 may be an important regulator of heart function. In case of human coronaviruses SARS and HCoV-NL63 infections, ACE-2 serve as functional receptor for the spike glycoprotein of both coronaviruses. ACE2 is activated by chloride and fluoride, but not bromide and Inhibited by MLN-4760, cFP_Leu, and EDTA, but not by the ACE inhibitors linosipril, captopril and enalaprilat. ACE2 is active from pH 6 to 9, and the optimum pH is 6.5 in the presence of 1 M NaCl.
- Poids moléculaire
- 109.8 kDa
- NCBI Accession
- NP_068576
- Pathways
- ACE Inhibitor Pathway, Peptide Hormone Metabolism, Regulation of Systemic Arterial Blood Pressure by Hormones, Feeding Behaviour
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