Sialoadhesin/CD169 Protein (AA 20-1641) (His tag)

N° du produit ABIN7013495

Détail du produit

Antigène: Sialoadhesin/CD169 (SIGLEC1) (Sialic Acid Binding Ig-Like Lectin 1, Sialoadhesin (SIGLEC1))

Type de proteíne: Recombinant

Attributs du protein: AA 20-1641

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette Sialoadhesin/CD169 protéine est marqué à la His tag.

Séquence: AA 20-1641

Attributs du produit: Cynomolgus Siglec-10 Protein, His Tag

Pureté: >95 % as determined by SDS-PAGE.

niveau d'endotoxine: Less than 1.0 EU per μg by the LAL method.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: MES,NaCl, pH 7.5

Stock: -20 °C

Détail du antigène

Antigène: Sialoadhesin/CD169 (SIGLEC1) (Sialic Acid Binding Ig-Like Lectin 1, Sialoadhesin (SIGLEC1))

Autre désignation: Siglec-1 (SIGLEC1 Produits)

Synonymes: Cd169 Protein, Siglec-1 Protein, Sn Protein, CD169 Protein, SIGLEC-1 Protein, SN Protein, dJ1009E24.1 Protein, SA Protein, SIGLEC1 Protein, p210 Protein, pSn Protein, sialic acid binding Ig like lectin 1 Protein, sialic acid binding Ig-like lectin 1, sialoadhesin Protein, SIGLEC1 Protein, Siglec1 Protein

Sujet: Alternate names for sialoadhesin include siglec-1 and CD169 (cluster of differentiation 169). Since sialoadhesin binds sialic acids with its N-terminal IgV-domain, it is also a member of the SIGLEC family. It is defined as an I-type lectin, since it contains 17 immunoglobulin (Ig) domains (one variable domain and 16 constant domains), and thus also belongs to the immunoglobulin superfamily (IgSF). Since sialoadhesin binds sialic acids with its N-terminal IgV-domain, it is also a member of the SIGLEC family. Acts as an endocytic receptor mediating clathrin dependent endocytosis. Macrophage-restricted adhesion molecule that mediates sialic-acid dependent binding to lymphocytes, including granulocytes, monocytes, natural killer cells, B-cells and CD8 T-cells. Preferentially binds to alpha-2,3-linked sialic acid. Binds to SPN/CD43 on T-cells.

Poids moléculaire: 175.1 kDa