Origine: SARS Coronavirus-2 (SARS-CoV-2)
Hôte: HEK-293 Cells
Recombinant
> 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Restrictions
For Research Use only
Format
Lyophilized
Buffer
Lyophilized from 0.22 μm filtered solution in PBS, 0.2 M Arginine, pH7.4. Normally trehalose is added as protectant before lyophilization.
Conseil sur la manipulation
Please avoid repeated freeze-thaw cycles.
Stock
-20 °C/-80 °C
Stockage commentaire
For long term storage, the product should be stored at lyophilized state at -20°C or lower.This product is stable after storage at: 4-8°C for 12 months in lyophilized state, -70°C for 3 months under sterile conditions after reconstitution.
E2 Protein, Surface Glycoprotein Protein, S Protein
Classe de substances
Viral Protein
Sujet
It's been reported that Coronavirus can infect the human respiratory epithelial cells through interaction with the human ACE2 receptor. The spike protein is a large type I transmembrane protein containing two subunits, S1 and S2. S1 mainly contains a receptor binding domain (RBD), which is responsible for recognizing the cell surface receptor. S2 contains basic elements needed for the membrane fusion.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity.