CD36 Protein (CD36) (AA 30-439) (Fc Tag)

N° du produit ABIN7092680

Cette protéine Recombinant CD36 est exprimée dans HEK-293 Cells.

Aperçu rapide pour CD36 Protein (CD36) (AA 30-439) (Fc Tag) (ABIN7092680)

Antigène: CD36

Type de proteíne: Recombinant

Origine: Humain

Source: HEK-293 Cells

Application: Affinity Measurement (AM), Antibody Drug Assay (ADA), Immunoassay (IA), Screening Assay (ScA)

Pureté: The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.

Détail du produit

Attributs du protein: AA 30-439

Purification/Conjugué: Cette CD36 protéine est marqué à la Fc Tag.

Fonction: Recombinant Human CD36 Protein with C-terminal human Fc tag

Specificité: CD36(Gly30-Asn439) hFc(Glu99-Ala330)

Attributs du produit: Extracellular Domain Protein

Purification: Purified from cell culture supernatant by affinity chromatography

Information d'application

Indications d'application: Extracellular Domain Proteins (ECD) can be used as:

• Immunogens for antibody drug development
• Reagents used for CAR-T positive cell monitoring
• Reagents for antibody screening and functional testing
• Reagents for antibody affinity measurement

Commentaires:

The protein was produced using HEK293 mammalian cell secretion expression system to ensure the close-to-native structures and post-translational modifications of the target protein.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Please see Certificate of Analysis for specific instructions of reconstitution.

Buffer: Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.

Stock: -20 °C,-80 °C

Stockage commentaire: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Date de péremption: 12 months

Détail du antigène

Antigène: CD36

Autre désignation: CD36

Sujet: BDPLT10,CHDS7,FAT,GP3B,GP4,GPIV,PASIV,SCARB3
The protein encoded by this gene is the fourth major glycoprotein of the platelet surface and serves as a receptor for thrombospondin in platelets and various cell lines. Since thrombospondins are widely distributed proteins involved in a variety of adhesive processes, this protein may have important functions as a cell adhesion molecule. It binds to collagen, thrombospondin, anionic phospholipids and oxidized LDL. It directly mediates cytoadherence of Plasmodium falciparum parasitized erythrocytes and it binds long chain fatty acids and may function in the transport and/or as a regulator of fatty acid transport. Mutations in this gene cause platelet glycoprotein deficiency. Multiple alternatively spliced transcript variants have been found for this gene.

Poids moléculaire: predicted molecular mass of 72.8 kDa after removal of the signal peptide.The apparent molecular mass of CD36-hFc is 100-130 kDa due to glycosylation.

UniProt: P16671

Pathways: Signalisation TLR, Peptide Hormone Metabolism, Response to Growth Hormone Stimulus, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Regulation of Lipid Metabolism by PPARalpha, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Hepatitis C, Toll-Like Receptors Cascades, Lipid Metabolism, S100 Proteins