CCR6 Protein (Fc Tag)

N° du produit ABIN7092813

Détail du produit

Antigène: CCR6 (Chemokine (C-C Motif) Receptor 6 (CCR6))

Type de proteíne: Recombinant

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette CCR6 protéine est marqué à la Fc Tag.

Fonction: Recombinant Human CCR6 with C-terminal human Fc tag

Specificité: CCR6 (Met1-Leu47) hFc (Glu99-Ala330)

Attributs du produit: Extracellular Domain Protein

Purification: affinity purification

Pureté: The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Reconstitute with deionized water

Buffer: Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.

Stock: -20 °C,-80 °C

Stockage commentaire: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Date de péremption: 12 months

Détail du antigène

Antigène: CCR6 (Chemokine (C-C Motif) Receptor 6 (CCR6))

Autre désignation: CCR6 (CCR6 Produits)

Synonymes: BN-1 Protein, C-C CKR-6 Protein, CC-CKR-6 Protein, CCR-6 Protein, CD196 Protein, CKR-L3 Protein, CKRL3 Protein, CMKBR6 Protein, DCR2 Protein, DRY6 Protein, GPR29 Protein, GPRCY4 Protein, STRL22 Protein, Cmkbr6 Protein, KY411 Protein, C-C motif chemokine receptor 6 Protein, chemokine (C-C motif) receptor 6 Protein, CCR6 Protein, Ccr6 Protein

Sujet: Synonymes: BN-1
Description: This gene encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. The gene is preferentially expressed by immature dendritic cells and memory T cells. The ligand of this receptor is macrophage inflammatory protein 3 alpha (MIP-3 alpha). This receptor has been shown to be important for B-lineage maturation and antigen-driven B-cell differentiation, and it may regulate the migration and recruitment of dentritic and T cells during inflammatory and immunological responses. Alternatively spliced transcript variants that encode the same protein have been described for this gene. [provided by RefSeq, Jul 2008]

Poids moléculaire: predicted molecular mass of 31.6 kDa after removal of the signal peptide. The apparent molecular mass of CCR6-hFc is 35-55 kDa due to glycosylation.

UniProt: P51684

Pathways: cAMP Metabolic Process