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ASXL1 Protein (GST tag)

ASXL1 Origine: Humain Hôte: Escherichia coli (E. coli) Recombinant > 90 % as determined by reducing SDS-PAGE.
N° du produit ABIN7319711
  • Antigène Voir toutes ASXL1 Protéines
    ASXL1 (Additional Sex Combs Like 1 (ASXL1))
    Type de proteíne
    Recombinant
    Origine
    • 5
    • 1
    Humain
    Source
    • 2
    • 2
    • 1
    • 1
    Escherichia coli (E. coli)
    Purification/Conjugué
    Cette ASXL1 protéine est marqué à la GST tag.
    Fonction
    Recombinant Human ASXL1 Protein (GST Tag)
    Séquence
    Lys1477-Arg154
    Attributs du produit
    Recombinant Human ASXL1 is produced by our E.coli expression system and the target gene encoding Lys1477-Arg1541 is expressed with a GST tag at the N-terminus.
    Pureté
    > 90 % as determined by reducing SDS-PAGE.
    niveau d'endotoxine
    < 1.0 EU per μg as determined by the LAL method.
    Top Product
    Discover our top product ASXL1 Protéine
  • Restrictions
    For Research Use only
  • Format
    Frozen, Liquid
    Buffer
    Supplied as a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.4.
    Stock
    -20 °C
    Stockage commentaire
    Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
  • Antigène
    ASXL1 (Additional Sex Combs Like 1 (ASXL1))
    Autre désignation
    ASXL1 (ASXL1 Produits)
    Synonymes
    asxl1 Protein, MGC83850 Protein, mKIAA0978 Protein, BOPS Protein, MDS Protein, additional sex combs like 1, transcriptional regulator L homeolog Protein, additional sex combs like 1, transcriptional regulator Protein, additional sex combs like 1 Protein, asxl1.L Protein, ASXL1 Protein, asxl1 Protein, Asxl1 Protein
    Sujet

    Background: Putative Polycomb group protein ASXL1 involved in transcriptional regulation mediated by ligand-bound nuclear hormone receptors, such as retinoic acid receptors (RARs) and peroxisome proliferator-activated receptor gamma (PPARG). It acts as coactivator of RARA and RXRA through association with NCOA1. ASXL1 also acts as corepressor through recruitment of KDM1A and CBX5 to target genes in a cell-type specific manner, the function seems to involve differential recruitment of methylated histone H3 to respective promoters.

    Synonym: Putative Polycomb group protein ASXL1, Additional sex combs-like protein 1, ASXL1, KIAA0978,

    Poids moléculaire
    33.6 kDa
    UniProt
    Q8IXJ9
    Pathways
    Retinoic Acid Receptor Signaling Pathway
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