ALDH1A3 Protein (His tag)
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- Antigène Voir toutes ALDH1A3 Protéines
- ALDH1A3 (Aldehyde Dehydrogenase 1 Family, Member A3 (ALDH1A3))
- Type de proteíne
- Recombinant
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Origine
- Humain
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Source
- Escherichia coli (E. coli)
- Purification/Conjugué
- Cette ALDH1A3 protéine est marqué à la His tag.
- Fonction
- Recombinant Human ALDH1A3 Protein (His Tag)
- Séquence
- Met1-Pro512
- Attributs du produit
- Recombinant Human ALDH1A3 is produced by our E.coli expression system and the target gene encoding Met1-Pro512 is expressed with a 6His tag at the N-terminus.
- Pureté
- > 95 % as determined by reducing SDS-PAGE.
- niveau d'endotoxine
- < 1.0 EU per μg as determined by the LAL method.
- Top Product
- Discover our top product ALDH1A3 Protéine
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- Restrictions
- For Research Use only
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- Format
- Frozen, Liquid
- Buffer
- Supplied as a 0.2 μm filtered solution of 20 mM TrisHCl,150 mMNaCl, pH 7.5,20 % Glycerol.
- Stock
- -20 °C
- Stockage commentaire
- Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
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- Antigène
- ALDH1A3 (Aldehyde Dehydrogenase 1 Family, Member A3 (ALDH1A3))
- Autre désignation
- ALDH1A3 (ALDH1A3 Produits)
- Synonymes
- RALDH3 Protein, ALDH1A3 Protein, ALDH1A6 Protein, ALDH6 Protein, MCOP8 Protein, Aldh6 Protein, V1 Protein, aldehyde dehydrogenase 1 family member A3 Protein, aldehyde dehydrogenase 1 family member A3 L homeolog Protein, aldehyde dehydrogenase 1 family, member A3 Protein, aldehyde dehydrogenase family 1, subfamily A3 Protein, ALDH1A3 Protein, aldh1a3.L Protein, aldh1a3 Protein, Aldh1a3 Protein
- Sujet
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Background: Aldehyde dehydrogenase 1 family member A3 (ALDH1A3), also known as retinaldehyde dehydrogenase 3 (RALDH3), is a member of the aldehyde dehydrogenase family known to metabolize a wide variety of aldehydes. ALDH1A3 specifically oxidizes retinal to retinoic acid (RA) and is differentially expressed in developing embryonic tissues and adult organs. The RA produced by ALDH1A3 in rodents contributes to the development of skin and hair follicles, brain, tooth buds, lungs, olfactory bulbs, kidneys, eyes, skeletal muscle and seminal vesicles. In recent research, ALDH1A3 could be as a marker of cancer stem cell to predict metastasis or clinical prognosis in many cancers.
Synonym: Aldehyde dehydrogenase family 1 member A3, ALDH1A3, Aldehyde dehydrogenase 6, Retinaldehyde dehydrogenase 3, RALDH-3, ALDH6,ALDH1A6,MCOP8,RALDH3
- Poids moléculaire
- 57.5 kDa
- UniProt
- P47895
- Pathways
- Retinoic Acid Receptor Signaling Pathway
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