ALDOB Protein (GST tag)

N° du produit ABIN7317289

Détail du produit

Antigène: ALDOB (Aldolase B, Fructose-Bisphosphate (ALDOB))

Type de proteíne: Recombinant

Origine: Humain

Source: Escherichia coli (E. coli)

Purification/Conjugué: Cette ALDOB protéine est marqué à la GST tag.

Fonction: Recombinant Human ALDOB/Aldolase B Protein (GST Tag)

Séquence: Ala 2-Tyr 364

Attributs du produit: A DNA sequence encoding the human ALDOB (P05062) (Ala 2-Tyr 364) was fused with the GST tag at the N-terminus.

Pureté: > 88 % as determined by reducing SDS-PAGE.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from sterile PBS, pH 7.5

Stock: 4 °C,-20 °C,-80 °C

Stockage commentaire: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Détail du antigène

Antigène: ALDOB (Aldolase B, Fructose-Bisphosphate (ALDOB))

Autre désignation: ALDOB/Aldolase B (ALDOB Produits)

Synonymes: aldb Protein, aldo2 Protein, xaldb Protein, ALDOB Protein, aldob Protein, ALDB Protein, ALDO2 Protein, Aldo-2 Protein, Aldo2 Protein, BC016435 Protein, LIV10 Protein, fb25f09 Protein, wu:fb25f09 Protein, aldolase B Protein, aldolase, fructose-bisphosphate B Protein, aldolase, fructose-bisphosphate B S homeolog Protein, aldolase b, fructose-bisphosphate Protein, aldolase B, fructose-bisphosphate Protein, xaldb Protein, aldob Protein, aldob.S Protein, ALDOB Protein, Aldob Protein

Sujet:

Background: UBE2G1 is a member of the ubiquitin-conjugating E2 family whose members perform the second step in the ubiquitination reaction. Initially identified as the main process for protein degradation; ubiquitination is believed nowadays to be crucial for a wider range of cellular processes. The outcome of the ubiquitin-conjugation reaction; and thereby the fate of the substrate; is heavily dependent on the number of ubiquitin molecules attached and how these ubiquitin molecules are inter-connected. To deal with this complexity and to allow adequate ubiquitination in time and space; a highly sophisticated conjugation machinery has been developed. In a sequential manner; ubiquitin becomes activated by an ubiquitin-activating enzyme (E1); which then transfers the ubiquitin to a group of ubiquitin-conjugating enzymes (E2s). Next; ubiquitin-loaded E2s are interacting with ubiquitin protein ligases (E3s) and ubiquitin is conjugated to substrates on recruitment by the E3. These three key enzymes are operating in a hierarchical system; wherein two E1s and 35 E2s have been found and hundreds of E3s have been identified in humans. 

Synonym: ALDB;ALDO2

Poids moléculaire: 66.5 kDa

UniProt: P05062