DAO Protein (His tag)

N° du produit ABIN7318403

Détail du produit

Antigène: DAO (ABP1) (Amiloride Binding Protein 1 (Amine Oxidase (Copper-Containing)) (ABP1))

Type de proteíne: Recombinant

Origine: Humain

Source: Human Cells

Purification/Conjugué: Cette DAO protéine est marqué à la His tag.

Fonction: Recombinant Human Diamine Oxidase/AOC1 Protein (His Tag)

Séquence: Glu20-Val751

Attributs du produit: Recombinant Human Amiloride-binding protein 1 is produced by our Mammalian expression system and the target gene encoding Glu20-Val751 is expressed with a 6His tag at the C-terminus.

Pureté: > 95 % as determined by reducing SDS-PAGE.

niveau d'endotoxine: < 1.0 EU per μg as determined by the LAL method.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Frozen, Liquid

Buffer: Supplied as a 0.2 μm filtered solution of 20 mM TrisHCl, 150 mM NaCl,10 % Glycerol, pH 7.5.

Stock: -20 °C

Stockage commentaire: Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.

Détail du antigène

Antigène: DAO (ABP1) (Amiloride Binding Protein 1 (Amine Oxidase (Copper-Containing)) (ABP1))

Autre désignation: Diamine Oxidase/AOC1 (ABP1 Produits)

Synonymes: ABP Protein, ABP1 Protein, DAO Protein, DAO1 Protein, KAO Protein, 1600012D06Rik Protein, Abp1 Protein, abp1 Protein, si:ch211-286c5.2 Protein, zgc:154101 Protein, Abp Protein, dao Protein, amine oxidase, copper containing 1 Protein, amine oxidase, copper-containing 1 Protein, AOC1 Protein, Aoc1 Protein, aoc1 Protein

Sujet:

Background: Amiloride-sensitive amine oxidase (AOC1) belongs to the copper/topaquinone oxidase family. The protein exists as homodimer by disulfide and mainly located in placenta and kidney. AOC1 catalyzes the degradation of compounds such as putrescine, histamine, spermine, and spermidine, substances involved in allergic and immune responses, cell proliferation, tissue differentiation, tumor formation, and possibly apoptosis. Placental DAO is thought to play a role in the regulation of the female reproductive function. The activity of this protein can be inhibited by amiloride in a competitive manner. It is inhibited by amiloride, a diuretic that acts by closing epithelial sodium ion channels.

Synonym: Amiloride-sensitive amine oxidase [copper-containing],DAO,Diamine oxidase,Amiloride-binding protein 1,Amine oxidase copper domain-containing protein 1,Histaminase,Kidney amine oxidase,KAO,AOC1,ABP1, DAO1

Poids moléculaire: 84.4 kDa

UniProt: P19801