APLP1 Protein (AA 1-580) (His tag)

N° du produit ABIN7317207

Détail du produit

Antigène: APLP1 (Amyloid beta (A4) Precursor-Like Protein 1 (APLP1))

Type de proteíne: Recombinant

Attributs du protein: AA 1-580

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette APLP1 protéine est marqué à la His tag.

Fonction: Recombinant Human APLP-1 Protein (aa 1-580, His Tag)

Séquence: Met 1-Glu580

Attributs du produit: A DNA sequence encoding the human APLP1 (P51693-1) (Met1-Glu580) was expressed with a polyhistidine tag at the C-terminus.

Pureté: > 95 % as determined by reducing SDS-PAGE.

niveau d'endotoxine: < 1.0 EU per μg as determined by the LAL method.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from sterile PBS, PH 7.4

Stock: 4 °C,-20 °C,-80 °C

Stockage commentaire: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Détail du antigène

Antigène: APLP1 (Amyloid beta (A4) Precursor-Like Protein 1 (APLP1))

Autre désignation: APLP-1 (APLP1 Produits)

Synonymes: aplp Protein, MGC115336 Protein, APLP Protein, Aplp1_retired Protein, RGD1561211 Protein, amyloid beta precursor like protein 1 Protein, amyloid beta precursor like protein 1 L homeolog Protein, amyloid beta (A4) precursor-like protein 1 Protein, APLP1 Protein, aplp1.L Protein, aplp1 Protein, Aplp1 Protein

Sujet:

Background: APLP1, also known as amyloid-like protein 1, is a member of the highly conserved amyloid precursor protein gene family. APLP1 is a membrane-associated glycoprotein that is cleaved by secretases in a manner similar to amyloid beta A4 precursor protein cleavage. APLP1, together with APLP2, are important modulators of glucose. APLP1 may also play a role in synaptic maturation during cortical development. Alternatively spliced transcript variants encoding different isoforms have been described. APLP1 also is a mammalian homologue of amyloid precursor protein (APP). APP is a type I membrane protein that is genetically linked to Alzheimer's disease.

Synonym: Amyloid-like protein 1, APLP, APLP-1, C30, APLP1

Poids moléculaire: 61.9 kDa

Pathways: cAMP Metabolic Process