APCS Protein (His tag)

N° du produit ABIN7319029

Détail du produit

Antigène: APCS (Amyloid P Component, Serum (APCS))

Type de proteíne: Recombinant

Origine: Humain

Source: Human Cells

Purification/Conjugué: Cette APCS protéine est marqué à la His tag.

Fonction: Recombinant Human APCS/SAP Protein (His Tag)

Séquence: His20-Val223

Attributs du produit: Recombinant Human Serum Amyloid P Component is produced by our Mammalian expression system and the target gene encoding His20-Val223 is expressed with a 6His tag at the C-terminus.

Pureté: > 95 % as determined by reducing SDS-PAGE.

niveau d'endotoxine: < 1.0 EU per μg as determined by the LAL method.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.2.

Stock: 4 °C,-20 °C,-80 °C

Stockage commentaire: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Détail du antigène

Antigène: APCS (Amyloid P Component, Serum (APCS))

Autre désignation: APCS/SAP (APCS Produits)

Synonymes: PTX2 Protein, SAP Protein, Sap Protein, APCS Protein, FP Protein, SAP(FP) Protein, apcs Protein, ptx2 Protein, sap Protein, amyloid P component, serum Protein, serum amyloid P-component Protein, amyloid P component, serum protein L homeolog Protein, APCS Protein, Apcs Protein, apcs.L Protein

Sujet:

Background: Serum Amyoid P Component (SAP) is a monomeric 25 kDa secreted serum glycoprotein that belongs to the pentraxins family. The members of pentaxin superfamily be characterised by calcium dependent ligand binding and distinctive flattened β-jellyroll structure similar to that of the legume lectins. SAP is a non-fibrillar component, it can interact with DNA and histones. It regulates the solubility of amyloid fibrils and protects them from degradation by proteolytic enzymes and phagocytic cells. SAP scavenge nuclear material released from damaged circulating cells. It has been proposed that SAP may function as an opsonin for a variety of ligands including autoantigens, apoptotic cells, chromatin and micro-organisms.

Synonym: Serum Amyloid P-Component, SAP, 9.5S Alpha-1-Glycoprotein, APCS, PT,STX2

Poids moléculaire: 24.2 kDa

UniProt: P02743