ASS1 Protein (His tag)
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- Antigène Voir toutes ASS1 Protéines
- ASS1 (Argininosuccinate Synthase 1 (ASS1))
- Type de proteíne
- Recombinant
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Origine
- Humain
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Source
- Escherichia coli (E. coli)
- Purification/Conjugué
- Cette ASS1 protéine est marqué à la His tag.
- Fonction
- Recombinant Human ASS1 Protein (His Tag)
- Séquence
- Met 1-Lys412
- Attributs du produit
- Recombinant Human Argininosuccinate Synthase is produced by our E.coli expression system and the target gene encoding Met1-Lys412 is expressed with a 6His tag at the N-terminus.
- Pureté
- > 95 % as determined by reducing SDS-PAGE.
- niveau d'endotoxine
- < 1.0 EU per μg as determined by the LAL method.
- Top Product
- Discover our top product ASS1 Protéine
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- Restrictions
- For Research Use only
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- Format
- Frozen, Liquid
- Buffer
- Supplied as a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, 50 mM Imidazole, 1 mM DTT, 40 % Glycerol, pH 7.5.
- Stock
- -20 °C
- Stockage commentaire
- Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
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- Antigène
- ASS1 (Argininosuccinate Synthase 1 (ASS1))
- Autre désignation
- ASS1 (ASS1 Produits)
- Synonymes
- ASS Protein, CTLN1 Protein, AA408052 Protein, Ass-1 Protein, fold Protein, ASSA Protein, Ass Protein, ass Protein, zgc:92051 Protein, wu:fb95a04 Protein, wu:fc01e08 Protein, argininosuccinate synthase 1 Protein, argininosuccinate synthetase 1 Protein, argininosuccinate synthase 1 S homeolog Protein, ASS1 Protein, Ass1 Protein, ass1.S Protein, ass1 Protein
- Sujet
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Background: Argininosuccinate Synthase (ASS1) is an urea cycle enzyme with a tetrameric structure composed of identical subunits. ASS1 is involved in the synthesis of arginine and catalyzes that condensation of citrulline and aspartate to argininosuccinate using ATP. ASS1 is important to the urea cycle as it catalyzes the important second last step in the arginine biosynthetic pathway. ASS1 mainly expressed in periportal hepatocytes, but also in most other body tissues. A deficiency of ASS1 causes citrullinemia (CTLN1), an autosomal recessive disease which is characterized by severe vomiting spells and mental retardation.
Synonym: Argininosuccinate Synthase, Citrulline--Aspartate Ligase, ASS1, ASS
- Poids moléculaire
- 42.8 kDa
- UniProt
- P00966
- Pathways
- Response to Growth Hormone Stimulus, Cellular Response to Molecule of Bacterial Origin
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