CLEC10A Protein (Fc Tag)

N° du produit ABIN7194472

Détail du produit

Antigène: CLEC10A (C-Type Lectin Domain Family 10, Member A (CLEC10A))

Type de proteíne: Recombinant

Origine: Souris

Source: HEK-293 Cells

Purification/Conjugué: Cette CLEC10A protéine est marqué à la Fc Tag.

Fonction: Recombinant Mouse CLEC10A/CD301 Protein (Fc Tag)

Séquence: Gln 58-Ser 305

Attributs du produit: A DNA sequence encoding the extracellular domain of mouse CLEC10A (NP_001191181.1) (Gln 58-Ser 305) was fused with the Fc region of human IgG1 at the N-terminus.

Pureté: > 86 % as determined by SDS-PAGE

niveau d'endotoxine: < 1.0 EU per μg of the protein as determined by the LAL method.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from sterile PBS, pH 7.4

Stock: 4 °C,-20 °C,-80 °C

Stockage commentaire: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Détail du antigène

Antigène: CLEC10A (C-Type Lectin Domain Family 10, Member A (CLEC10A))

Autre désignation: CLEC10A/CD301 (CLEC10A Produits)

Synonymes: CLEC10A Protein, CD301 Protein, CLECSF13 Protein, CLECSF14 Protein, HML Protein, HML2 Protein, MGL Protein, CD301a Protein, M-ASGP-BP-1 Protein, Mgl Protein, Mgl1 Protein, Mgll Protein, C-type lectin domain family 10 member A Protein, C-type lectin domain containing 10A Protein, C-type lectin domain family 10, member A Protein, LOC607405 Protein, CLEC10A Protein, Clec10a Protein

Sujet:

Background: CLEC10A, also known as the macrophage galactose-type calcium-type lectins (MGLs, CD301) constitute a unique class of C-type lectins because of their specificity for galactose and its structural homologues. MGLs/CD301 is a type II transmembrane glycoproteins and is expressed on macrophages and related cells of myeloid origins, particularly immature dendritic cells (DCs). There are 2 homologues: MGL1 and MGL2 (CD301a and CD301b) in mice. MGL1/CD301a induces both the production and secretion of interleukin (IL)-10. MGL1/CD301a plays a protective role against colitis by effectively inducing IL-10 production by colonic lamina propria macrophages in response to invading commensal bacteria.

Synonym: CD301a,M-ASGP-BP-1,Mgl,Mgl1

Poids moléculaire: 56.7 kDa

NCBI Accession: NP_001191181