CA8 Protein (His tag)

N° du produit ABIN7194579

Détail du produit

Antigène: CA8 (Carbonic Anhydrase VIII (CA8))

Type de proteíne: Recombinant

Activité biologique: Active

Origine: Humain

Source: Escherichia coli (E. coli)

Purification/Conjugué: Cette CA8 protéine est marqué à la His tag.

Fonction: Recombinant Human Carbonic Anhydrase 8/CA8 Protein (His Tag)(Active)

Séquence: Met 1-Gln 290

Attributs du produit: A DNA sequence encoding the human CA8 (NP_004047.3) (Met 1-Gln 290) was expressed, with a polyhistidine tag at the C-terminus.

Pureté: > 94 % as determined by reducing SDS-PAGE.

Biological Activity Comment: Measured by its esterase activity. The specific activity is >100 pmoles/min/μg.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from sterile PBS, 15 % glycerol, pH 7.5

Stock: 4 °C,-20 °C,-80 °C

Stockage commentaire: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Détail du antigène

Antigène: CA8 (Carbonic Anhydrase VIII (CA8))

Autre désignation: Carbonic Anhydrase 8/CA8 (CA8 Produits)

Synonymes: AW546993 Protein, Ca8 Protein, Cals Protein, Cals1 Protein, Carp Protein, wdl Protein, zgc:110118 Protein, CA-VIII Protein, CALS Protein, CAMRQ3 Protein, CARP Protein, carbonic anhydrase 8 Protein, carbonic anhydrase VIII Protein, CAH8 Protein, Car8 Protein, ca8 Protein, CA8 Protein

Sujet:

Background: The carbonic anhydrases (or carbonate dehydratases) are classified as metalloenzyme for its zinc ion prosthetic group and form a family of enzymes that catalyze the rapid interconversion of carbon dioxide and water to bicarbonate and protons, a reversible reaction that takes part in maintaining acid-base balance in blood and other tissues. The carbonic anhydrasekl (CA) family consists of at least 11 enzymatically active members and a few inactive homologous proteins. Carbonic anhydrase protein (CA) VIII, which is a member of the CA gene family, has been shown to have no catalytic CA activity and its biological function is still unknown. Increased expression of CA-RP VIII was observed in 78 % of colorectal carcinomas. It suggested that CA-RP VIII plays a role in the process of invasion in colorectal cancer.

Synonym: Carbonic Anhydrase-Related Protein, CARP, Carbonic Anhydrase VIII, CA-VIII, CA8, CALS,CAMRQ3,MGC120502,MGC99509

Poids moléculaire: 33.8 kDa

NCBI Accession: NP_004047