CD200R4 Protein (Fc Tag)

N° du produit ABIN7320209

Détail du produit

Antigène: CD200R4 (CD200 Receptor 4 (CD200R4))

Type de proteíne: Recombinant

Origine: Souris

Source: HEK-293 Cells

Purification/Conjugué: Cette CD200R4 protéine est marqué à la Fc Tag.

Fonction: Recombinant Mouse CD200R4/CD200RLa Protein (Fc Tag)

Séquence: Met 1-Thr 241

Attributs du produit: A DNA sequence encoding the extracellular domain of mouse CD200R4 (NP_997127.1) (Met 1-Thr 241) was fused with the Fc region of human IgG1 at the C-terminus.

Pureté: > 94 % as determined by SDS-PAGE

niveau d'endotoxine: < 1.0 EU per μg of the protein as determined by the LAL method.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from sterile PBS, pH 7.4

Stock: 4 °C,-20 °C,-80 °C

Stockage commentaire: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Détail du antigène

Antigène: CD200R4 (CD200 Receptor 4 (CD200R4))

Autre désignation: CD200R4/CD200RLa (CD200R4 Produits)

Synonymes: F630107N04Rik Protein, MCD200RLa Protein, CD200 receptor 4 Protein, Cd200r4 Protein

Sujet:

Background: Cell surface glycoprotein CD200 receptor 4, also known as Cell surface glycoprotein OX2 receptor 4, CD200 cell surface glycoprotein receptor-like 4, CD200RLa, and CD200R4, is a single-pass type I  membrane protein which belongs to the CD200R family. CD200 (OX2) is a cell surface glycoprotein that interacts with a structurally related receptor (CD200R) expressed mainly on myeloid cells and is involved in regulation of macrophage and mast cell function. In mouse there are up to five genes related to CD200R with conflicting data as to whether they bind CD200. CD200R4 contains one Ig-like C2-type (immunoglobulin-like) domain and one Ig-like V-type (immunoglobulin-like) domain. CD200R4 is highly expressed in monocytes, NK cells and a subset of NKT cells. It is weakly expressed in granulocytes and B cells (at protein level). CD200R4 is also expressed in brain, lung, testis, thymus, intestine and uterus. and in bone marrow derived-macrophage and dendritic cells and mast cells. CD200R4 is involved in the recruitment or surface expression of the TYROBP receptor.

Synonym: Cd200r4;F630107N04Rik;MCD200RLa;CD200 Receptor 4

Poids moléculaire: 50.6 kDa

NCBI Accession: NP_997127