CXCL6 Protein (His tag)

N° du produit ABIN7319813

Détail du produit

Antigène: CXCL6 (Chemokine (C-X-C Motif) Ligand 6 (CXCL6))

Type de proteíne: Recombinant

Origine: Humain

Source: Human Cells

Purification/Conjugué: Cette CXCL6 protéine est marqué à la His tag.

Fonction: Recombinant Human C-X-C Motif Chemokine 6/CXCL6 (C-6His)

Séquence: Gly38-Asn114

Attributs du produit: Recombinant Human C-X-C Motif Chemokine 6 is produced by our Mammalian expression system and the target gene encoding Gly38-Asn114 is expressed with a 6His tag at the C-terminus.

Pureté: >95 % as determined by reducing SDS-PAGE.

niveau d'endotoxine: < 1.0 EU per μg as determined by the LAL method.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, 5 % Trehalose, pH 7.4.

Stock: 4 °C,-20 °C,-80 °C

Stockage commentaire: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Détail du antigène

Antigène: CXCL6 (Chemokine (C-X-C Motif) Ligand 6 (CXCL6))

Autre désignation: C-X-C Motif Chemokine 6/CXCL6 (CXCL6 Produits)

Synonymes: CKA-3 Protein, GCP-2 Protein, GCP2 Protein, SCYB6 Protein, Cxcl6 Protein, CXCL5 Protein, C-X-C motif chemokine ligand 6 Protein, chemokine (C-X-C motif) ligand 5 Protein, CXCL6 Protein, Cxcl6 Protein, CXCL5 Protein

Sujet:

Background: Chemokine (C-X-C-Motif) Ligand 6 (CXCL6) is a small cytokine belonging to the CXC chemokine family. It is a potent neutrophil chemotactic and activating factor and it exhibits extensive similarity to other CXC chemokines such as IL-8 and ENA-78. CXCL6 can promote the release of MMP-9 from granulocytes indicating its potential role as an inflammatory mediator. It functionally uses both of the IL-8/CXCL8 receptors to chemoattract neutrophils but that is structurally most related to epithelial cell-derived neutrophil attractant-78 (ENA-78)/CXCL5. The human CXCL6 gene has been cloned and is physically mapped to the CXC chemokine locus on chromosome 4. Mature human CXCL6 is a 75 amino acid (aa) protein with a predicted molecular weight of approximately 8 kDa. Human CXCL6 shares 60 % and 67 % aa identity with mouse and bovine CXCL6, respectively.

Synonym: C-X-C Motif Chemokine 6, Chemokine Alpha 3, CKA-3, Granulocyte Chemotactic Protein 2, GCP-2, Small-Inducible Cytokine B6, CXCL6, GCP2, SCYB6

Poids moléculaire: 9.35 kDa

UniProt: P80162