COL4a3 Protein (Fc Tag)

N° du produit ABIN7321080

Détail du produit

Antigène: COL4a3 (COL4A3) (Collagen, Type IV, alpha 3 (COL4A3))

Type de proteíne: Recombinant

Origine: Rat

Source: HEK-293 Cells

Purification/Conjugué: Cette COL4a3 protéine est marqué à la Fc Tag.

Fonction: Recombinant Rat COL4A3 Protein (Fc Tag)

Séquence: Gly1426-His1670

Attributs du produit: A DNA sequence encoding the rat COL4A3 (NP_001129231) (Gly1426-His1670) was expressed with Fc region of human IgG1 at the N-terminus.

Pureté: > 85 % as determined by SDS-PAGE

niveau d'endotoxine: < 1.0 EU per μg of the protein as determined by the LAL method

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from sterile PBS, pH 7.4

Stock: 4 °C,-20 °C,-80 °C

Stockage commentaire: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Détail du antigène

Antigène: COL4a3 (COL4A3) (Collagen, Type IV, alpha 3 (COL4A3))

Autre désignation: COL4A3 (COL4A3 Produits)

Synonymes: zTumstatin Protein, [a]3(IV) Protein, alpha3(IV) Protein, collagen type IV alpha 3 chain Protein, collagen, type IV, alpha 3 Protein, COL4A3 Protein, col4a3 Protein, Col4a3 Protein

Sujet:

Background: COL4A3 is a major structural component of basement membranes. It is composed of 3 alpha subunits, which are encoded by 6 different genes, alpha 1 through alpha 6. Each of these alpha subunits can form a triple helix structure with 2 other subunits to form COL4A3. Autoantibodies bind to the collagen molecules in the basement membranes of alveoli and glomeruli can cause goodpasture syndrome. COL4A3 is also linked to an autosomal recessive form of alport syndrome. COL4A3 is organized in a head-to-head conformation and each gene pair shares a common promoter.

Synonym: COL4A3

Poids moléculaire: 55.2 kDa

NCBI Accession: NP_001129231

Pathways: Sensory Perception of Sound, Positive Regulation of Endopeptidase Activity