COLEC11 Protein (His tag)

N° du produit ABIN7318324

Détail du produit

Antigène: COLEC11 (Collectin Sub-Family Member 11 (COLEC11))

Type de proteíne: Recombinant

Origine: Humain

Source: Human Cells

Purification/Conjugué: Cette COLEC11 protéine est marqué à la His tag.

Fonction: Recombinant Human Collectin-11/COLEC11 Protein (His Tag)

Séquence: Gln26-Met271

Attributs du produit: Recombinant Human Collectin-11 is produced by our Mammalian expression system and the target gene encoding Gln26-Met271 is expressed with a 6His tag at the C-terminus.

Pureté: > 95 % as determined by reducing SDS-PAGE.

niveau d'endotoxine: < 1.0 EU per μg as determined by the LAL method.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from a 0.2 μm filtered solution of 20 mM PB,150 mM NaCl, pH 7.4.

Stock: 4 °C,-20 °C,-80 °C

Stockage commentaire: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Détail du antigène

Antigène: COLEC11 (Collectin Sub-Family Member 11 (COLEC11))

Autre désignation: Collectin-11/COLEC11 (COLEC11 Produits)

Synonymes: COLEC11 Protein, 3MC2 Protein, CL-K1-I Protein, CL-K1-II Protein, CL-K1-IIa Protein, CL-K1-IIb Protein, CLK1 Protein, 1010001H16Rik Protein, wu:fb82e09 Protein, zgc:103572 Protein, collectin subfamily member 11 Protein, collectin sub-family member 11 Protein, collectin subfamily member 11 L homeolog Protein, COLEC11 Protein, Colec11 Protein, colec11 Protein, colec11.L Protein

Sujet:

Background: Collectin-11 is a secreted protein that belongs to the COLEC10/COLEC11 family. Collectin-11 contains one C-type lectin domain and one collagen-like domain. Collectins play important roles in the innate immune system by binding to carbohydrate antigens on microorganisms, facilitating their recognition and removal. Collectin-11 binds to various sugars including fucose and mannose, but does not bind to glucose, N-acetylglucosamine and N-acetylgalactosamine. It has a higher affinity for fucose compared to mannose. Collectin-11 binds lipopolysaccharides (LPS). It also involved in fundamental development serving as a guidance cue for neural crest cell migration. Defects in Collectin-11 are the cause of 3MC syndrome type 2 (3MC2).

Synonym: Collectin-11, Collectin Kidney Protein 1, CL-K1, COLEC11

Poids moléculaire: 27.1 kDa

UniProt: Q9BWP8