CUTC Protein (His tag)

N° du produit ABIN7317556

Détail du produit

Antigène: CUTC (CutC Copper Transporter Homolog (CUTC))

Type de proteíne: Recombinant

Origine: Humain

Source: Escherichia coli (E. coli)

Purification/Conjugué: Cette CUTC protéine est marqué à la His tag.

Fonction: Recombinant Human CUTC/CGI-32 Protein (His Tag)

Séquence: Met 1-Val 273

Attributs du produit: A DNA sequence encoding the human CUTC (Q9NTM9) (Met 1-Val 273) was expressed, with an N-terminal polyhistidine tag.

Pureté: > 92 % as determined by reducing SDS-PAGE.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from sterile PBS, 10 % glycerol, pH 7.4

Stock: 4 °C,-20 °C,-80 °C

Stockage commentaire: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Détail du antigène

Antigène: CUTC (CutC Copper Transporter Homolog (CUTC))

Autre désignation: CUTC/CGI-32 (CUTC Produits)

Synonymes: zgc:103406 Protein, RP11-483F11.3 Protein, 2310039I18Rik Protein, AI326282 Protein, CGI-32 Protein, cutC copper transporter Protein, cutC copper transporter homolog (E. coli) Protein, CUTC Protein, cutc Protein, Cutc Protein

Sujet:

Background: Copper homeostasis protein cutC homolog, also known as CGI-32 and CUTC, is a cytoplasm and nucleus protein which belongs to the CutC family. CUTC may play a role in copper homeostasis. It can bind one Cu1+ per subunit. Copper is an essential trace element to life and particularly plays a pivotal role in the physiology of aerobic organisms. Copper is a micronutrient that is required for proper metabolic functioning of most prokaryotic and eukaryotic organisms. To sustain an adequate supply of copper, a cell requires molecular mechanisms that control the metal content to avoid copper toxicity. This toxicity comes primarily from the reactivity of copper, which can lead to the generation of free radicals. In bacteria, two independent systems are responsible for maintaining the balance of copper within the cells ( Cop and Cut family proteins ). The Cut protein family is associated with copper homeostasis and involved in uptake, storage, delivery, and efflux of copper. CutC is a member of the Cut family and is suggested to be involved in efflux trafficking of cuprous ion. CutC is able to respond transcriptionally to copper and to participate in the control of copper homeostasis in E. faecalis.

Synonym: CGI-32

Poids moléculaire: 31 kDa

UniProt: Q9NTM9

Pathways: Transition Metal Ion Homeostasis