CSRP1 Protein (His tag)

N° du produit ABIN7317625

Détail du produit

Antigène: CSRP1 (Cysteine and Glycine-Rich Protein 1 (CSRP1))

Type de proteíne: Recombinant

Origine: Humain

Source: Escherichia coli (E. coli)

Purification/Conjugué: Cette CSRP1 protéine est marqué à la His tag.

Fonction: Recombinant Human CSRP1 Protein (His Tag)

Séquence: Met 1-Glu 193

Attributs du produit: A DNA sequence encoding the human CSRP1 (NP_004069.1) (Met 1-Glu 193) was expressed, with a polyhistide tag at the C-terminus.

Pureté: > 95 % as determined by reducing SDS-PAGE.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from sterile 10 mM Na2HPO4, 2 mM KH2PO4, 2.7 mM KCl, 500 mM NaCl, pH 7.4

Stock: 4 °C,-20 °C,-80 °C

Stockage commentaire: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Détail du antigène

Antigène: CSRP1 (Cysteine and Glycine-Rich Protein 1 (CSRP1))

Autre désignation: CSRP1 (CSRP1 Produits)

Synonymes: CRP Protein, CRP1 Protein, CSRP Protein, CYRP Protein, D1S181E Protein, AA408841 Protein, AA959891 Protein, AW545626 Protein, Csrp Protein, cb796 Protein, csrp1 Protein, zgc:77332 Protein, MGC85577 Protein, MGC89932 Protein, CSRP1 Protein, zgc:158737 Protein, cysteine and glycine rich protein 1 Protein, cysteine and glycine-rich protein 1 Protein, cysteine and glycine-rich protein 1a Protein, cysteine and glycine rich protein 1 L homeolog Protein, cysteine and glycine-rich protein 1b Protein, Cysteine and glycine-rich protein 1 Protein, CSRP1 Protein, Csrp1 Protein, csrp1a Protein, csrp1.L Protein, csrp1 Protein, csrp1b Protein, LOC100304834 Protein, Tsp_01053 Protein

Sujet:

Background: Cysteine and glycine-rich protein 1, also known as Cysteine-rich protein 1, CSRP1 and CSRP, is a member of the CSRP family which may be involved in regulatory processes important for development and cellular differentiation. CSRP1 contains two LIM zinc-binding domains. The LIM / double zinc-finger motif found in CSRP1 is found in a group of proteins with critical functions in gene regulation, cell growth, and somatic differentiation. Zebrafish CSRP1 is expressed in the mesendoderm and its derivatives. CSRP1 interacts with Dishevelled 2 (Dvl2) and Diversin (Div), which control cell morphology and other dynamic cell behaviors via the noncanonical Wnt and JNK pathways. When CSRP1 message is knocked down, abnormal convergent extension cell movement is induced, resulting in severe deformities in midline structures. In addition, cardiac bifida is induced as a consequence of defects in cardiac mesoderm cell migration. CSRP1 acts as a key molecule of the noncanonical Wnt pathway, which orchestrates cell behaviors during dynamic morphogenetic movements of tissues and organs.

Synonym: CRP;CRP1;CSRP;CYRP;D1S181E;HEL-141

Poids moléculaire: 21.4 kDa

NCBI Accession: NP_004069