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CYB5R1 Protein (His tag)

CYB5R1 Origine: Humain Hôte: Escherichia coli (E. coli) Recombinant > 97 % as determined by reducing SDS-PAGE.
N° du produit ABIN7317282
  • Antigène Voir toutes CYB5R1 Protéines
    CYB5R1 (Cytochrome B5 Reductase 1 (CYB5R1))
    Type de proteíne
    Recombinant
    Origine
    • 5
    • 1
    • 1
    • 1
    • 1
    Humain
    Source
    • 2
    • 2
    • 2
    • 2
    • 1
    Escherichia coli (E. coli)
    Purification/Conjugué
    Cette CYB5R1 protéine est marqué à la His tag.
    Fonction
    Recombinant Human CYB5R1 Protein (His Tag)
    Séquence
    Leu 29-Tyr 305
    Attributs du produit
    A DNA sequence encoding the human CYB5R1 (Q9UHQ9) (Leu 29-Tyr 305) was expressed, with a polyhistidine tag at the N-terminus.
    Pureté
    > 97 % as determined by reducing SDS-PAGE.
    Top Product
    Discover our top product CYB5R1 Protéine
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Please refer to the printed manual for detailed information.
    Buffer
    Lyophilized from sterile PBS, pH 7.4
    Stock
    4 °C,-20 °C,-80 °C
    Stockage commentaire
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • Antigène
    CYB5R1 (Cytochrome B5 Reductase 1 (CYB5R1))
    Autre désignation
    CYB5R1 (CYB5R1 Produits)
    Synonymes
    B5R.1 Protein, B5R1 Protein, B5R2 Protein, NQO3A2 Protein, humb5R2 Protein, 1500005G05Rik Protein, C80155 Protein, Nqo3a2 Protein, NAD(P)H:quinone oxidoreductase type 3, polypeptide A2 Protein, cytochrome b5 reductase 1 Protein, CYB5R1 Protein, Cyb5r1 Protein
    Sujet

    Background: Tyrosinase-related protein 1, also known as TYRP1 or TRP1, is a melanosomal enzyme that belongs to the tyrosinase family and plays an important role in the melanin biosynthetic pathway. Mutations in this enzyme are the cause of rufous oculocutaneous albinism and oculocutaneous albinism type III. TYRP1 / TRP1 is involved in the oxidation of 5,6-dihydroxyindole-2-carboxylic acid (DHICA) into indole-5,6-quinone-2-carboxylic acid. This enzyme may regulate or influence the type of melanin synthesized. The expression of Tyrosinase-related protein 1 (TYRP1) is regulated by the microphthalmia-associated transcription factor (MITF). There is mounting evidence demonstrating that in addition to its role in eumelanin synthesis, TYRP1 is involved in maintaining stability of tyrosinase proliferation and melanocyte cell death.

    Synonym: B5R.1,B5R1,B5R2,humb5R2,NQO3A2,PRO9865,UNQ3049

    Poids moléculaire
    33.5 kDa
    UniProt
    Q9UHQ9
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