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Decorin Protein (DCN) (His tag)

DCN Origine: Souris Hôte: Human Cells Recombinant > 95 % as determined by SDS-PAGE
N° du produit ABIN7320511
  • Antigène Voir toutes Decorin (DCN) Protéines
    Decorin (DCN)
    Type de proteíne
    Recombinant
    Origine
    • 15
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Souris
    Source
    • 8
    • 6
    • 4
    • 3
    • 2
    • 1
    • 1
    Human Cells
    Purification/Conjugué
    Cette Decorin protéine est marqué à la His tag.
    Fonction
    Recombinant Mouse Decorin/DCN Protein (His Tag)
    Séquence
    Gly17-Lys354
    Attributs du produit
    Recombinant Mouse Decorin is produced by our Mammalian expression system and the target gene encoding Gly17-Lys354 is expressed with a 6His tag at the C-terminus.
    Pureté
    > 95 % as determined by SDS-PAGE
    niveau d'endotoxine
    < 1.0 EU per μg as determined by the LAL method.
    Top Product
    Discover our top product DCN Protéine
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Please refer to the printed manual for detailed information.
    Buffer
    Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
    Stock
    4 °C,-20 °C,-80 °C
    Stockage commentaire
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • Antigène
    Decorin (DCN)
    Autre désignation
    Decorin/DCN (DCN Produits)
    Synonymes
    CSCD Protein, DSPG2 Protein, PG40 Protein, PGII Protein, PGS2 Protein, SLRR1B Protein, DC Protein, mDcn Protein, cscd Protein, dspg2 Protein, pg40 Protein, pgii Protein, pgs2 Protein, slrr1b Protein, decorin Protein, decorin L homeolog Protein, DCN Protein, Dcn Protein, dcn.L Protein, dcn Protein
    Sujet

    Background: Decorin, also known as PG40 and DCN, is a member of the class I family of small leucine-rich proteoglycans (SLRPs) that is expressed in the stroma of various forms of cancer and has been recently proposed to act as a guardian from the matrix. Mature human Decorin contains 12 tandem LRR and shares 80 % and 78 % aa sequence identity with mouse and rat Decorin, respectively. Decorin embraces numerous functions including: regulation of collagen fibrillogenesis, hepatic carcinogenesis, fetal membrane and calcium homeostasis, keratinocyte function, and suppression of angiogenesis. Most recently, soluble decorin has been shown to induce autophagy in endothelial cells and mitophagy in breast carcinoma cells.

    Synonym: Decorin, Bone proteoglycan II, PG-S2, PG40, Dcn

    Poids moléculaire
    39.0 kDa
    UniProt
    P28654
    Pathways
    Glycosaminoglycan Metabolic Process
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