RNASE3 Protein (His tag)

N° du produit ABIN7318990

Détail du produit

Antigène: RNASE3 (ECP) (Eosinophil Cationic Protein (ECP))

Type de proteíne: Recombinant

Origine: Humain

Source: Human Cells

Purification/Conjugué: Cette RNASE3 protéine est marqué à la His tag.

Fonction: Recombinant Human Ribonuclease 3/RNASE3 Protein (His Tag)

Séquence: Arg28-Ile160

Attributs du produit: Recombinant Human Ribonuclease 3 is produced by our Mammalian expression system and the target gene encoding Arg28-Ile160 is expressed with a 6His tag at the C-terminus.

Pureté: > 95 % as determined by reducing SDS-PAGE.

niveau d'endotoxine: < 1.0 EU per μg as determined by the LAL method.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Frozen, Liquid

Buffer: Supplied as a 0.2 μm filtered solution of 20 mM TrisHCl,150 mM NaCl,1 mMDTT,10 % Glycerol, pH 7.5.

Stock: -20 °C

Stockage commentaire: Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.

Détail du antigène

Antigène: RNASE3 (ECP) (Eosinophil Cationic Protein (ECP))

Autre désignation: Ribonuclease 3/RNASE3 (ECP Produits)

Synonymes: ECP Protein, RNS3 Protein, ribonuclease A family member 3 Protein, RNASE3 Protein

Sujet:

Background: Ribonuclease 3 (RNASE3) is a basic protein that is localized to the eosinophil primary matrix and belongs to the pancreatic ribonuclease family. RNASE3 is released during degranulation of eosinophils. RNASE3 possesses a wide variety of biological activities. RNASE3 interacts with bacterial lipopolysaccharide (LPS) and lipoteichoic acid (LTA). RNASE3 exhibits antibacterial activity, including cytoplasmic membrane depolarization of preferentially Gram-negative, but also Gram-positive strains. It promotes E. coli outer membrane detachment, alteration of the overall cell shape and partial loss of cell content.

Synonym: Eosinophil Cationic Protein, ECP, Ribonuclease 3, RNase 3, RNASE3, ECP, RNS3

Poids moléculaire: 16.6 kDa

UniProt: P12724