FAM19A4 Protein (His tag)

N° du produit ABIN7318954

Détail du produit

Antigène: FAM19A4 (Family with Sequence Similarity 19 (Chemokine (C-C Motif)-Like), Member A4 (FAM19A4))

Type de proteíne: Recombinant

Origine: Humain

Source: Escherichia coli (E. coli)

Purification/Conjugué: Cette FAM19A4 protéine est marqué à la His tag.

Fonction: Recombinant Human FAM19A4 Protein (His Tag)

Séquence: Ser35-Arg140

Attributs du produit: Recombinant Human Family with Sequence Similarity 19, Member A4 is produced by our E.coli expression system and the target gene encoding Ser35-Arg140 is expressed with a 6His tag at the N-terminus.

Pureté: > 95 % as determined by reducing SDS-PAGE.

niveau d'endotoxine: < 1.0 EU per μg as determined by the LAL method.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from a 0.2 μm filtered solution of 20 mM PB,150 mM NaCl, pH 7.4.

Stock: 4 °C,-20 °C,-80 °C

Stockage commentaire: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Détail du antigène

Antigène: FAM19A4 (Family with Sequence Similarity 19 (Chemokine (C-C Motif)-Like), Member A4 (FAM19A4))

Autre désignation: FAM19A4 (FAM19A4 Produits)

Synonymes: TAFA-4 Protein, TAFA4 Protein, C130034I18Rik Protein, Fam19a4 Tafa-4 Protein, Tafa-4 Protein, family with sequence similarity 19 member A4, C-C motif chemokine like Protein, family with sequence similarity 19, member A4 Protein, FAM19A4 Protein, Fam19a4 Protein

Sujet:

Background: FAM19A4 is a secreted, 12 kDa member of the FAM19/TAFA family of chemokine-like proteins. Like other members of the FAM19/TAFA family, with the exception of TAFA5, mature FAM19A4 contains 10 regularly spaced cysteine residues. The FAM19A4 proteins are predominantly expressed in specific regions of the brain and the biological functions of FAM19A4 family members remain to be determined, but there are a few tentative hypotheses. First, FAM19A4 may modulate immune responses in the CNS by functioning as brain specific chemokines, and may act with other chemokines to optimize the recruitment and activity of immune cells in the CNS. Second, FAM19A4 may represent a novel class of neurokines that act as regulators of immune nervous cells. And third, FAM19A4 may control axonal sprouting following brain injury.

Synonym: Protein FAM19A4,Chemokine-like protein TAFA-4,TAFA4,family with sequence similarity 19 (chemokine (C-C motif)-like), member A4, FAM19A4, chemokine-like protein TAFA-4

Poids moléculaire: 14.1 kDa

UniProt: Q96LR4