FGL1 Protein (His tag)

N° du produit ABIN7321019

Détail du produit

Antigène: FGL1 (Fibrinogen-Like 1 (FGL1))

Type de proteíne: Recombinant

Activité biologique: Active

Origine: Cynomolgus

Source: Human Cells

Purification/Conjugué: Cette FGL1 protéine est marqué à la His tag.

Fonction: Recombinant Cynomolgus FGL1 (C-6His)

Séquence: Leu23-Ile312

Attributs du produit: Recombinant Cynomolgus Fibrinogen-like Protein 1 is produced by our Mammalian expression system and the target gene encoding Leu23-Ile312 is expressed with a 6His tag at the C-terminus.

Pureté: >95 % as determined by reducing SDS-PAGE.

niveau d'endotoxine: < 1.0 EU per μg as determined by the LAL method.

Biological Activity Comment: Loaded Cynomolgus LAG-3-Fc(Cat#PKSQ050015) on Protein A Biosensor, can bind Cynomolgus FGL1-His(Cat#PKSQ050095) with an affinity constant of 28.6nM as determined in BLI assay.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Frozen, Liquid

Buffer: Supplied as a 0.2 μm filtered solution of 20 mM Tris-HCl, 300 mM NaCl, 10 % Glycerol, 2 mM EDTA, pH 8.0.

Stock: -20 °C

Stockage commentaire: Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.

Détail du antigène

Antigène: FGL1 (Fibrinogen-Like 1 (FGL1))

Autre désignation: FGL1 (FGL1 Produits)

Synonymes: MGC84748 Protein, FGL1 Protein, DKFZp470A2333 Protein, Frep1 Protein, Lfire1 Protein, HFREP1 Protein, HP-041 Protein, LFIRE-1 Protein, LFIRE1 Protein, Mfire1 Protein, fibrinogen like 1 L homeolog Protein, fibrinogen like 1 Protein, fibrinogen-like 1 Protein, fibrinogen-like protein 1 Protein, fgl1.L Protein, FGL1 Protein, Fgl1 Protein

Sujet:

Background: Hepassocin, also known as hepatocyte-derived fibrinogen-related protein 1 (HFREP-1), is a liver-specific secreted protein belonging to the fibronogen superfamily, whose members share a fibrinogen domain at their C-termini. It is secreted by the liver and functions as a mitogen for hepatocytes. Hepassocin may play a role in the development of hepatocellular carcinomas. Hepassocin is a disulfide-linked homodimeric protein with a C-terminal fibrinogen domain. It is reported that it is a major immune inhibitory ligand of LAG-3 .

Synonym: Angiopoietin-related protein 4, 425O18-1, Angiopoietin-like protein 4, Fasting-induced adipose factor, Hepatic fibrinogen/angiopoietin-related protein, HFARP, Secreted protein Bk89, Angptl4, Farp, Fiaf, Ng27

Poids moléculaire: 34.8 kDa

UniProt: A0A2K5X990