FAH Protein (His tag)

N° du produit ABIN7318508

Détail du produit

Antigène: FAH (Fumarylacetoacetate Hydrolase (Fumarylacetoacetase) (FAH))

Type de proteíne: Recombinant

Origine: Humain

Source: Human Cells

Purification/Conjugué: Cette FAH protéine est marqué à la His tag.

Fonction: Recombinant Human Fumarylacetoacetase/FAH Protein (His Tag)

Séquence: Ser2-Ser419

Attributs du produit: Recombinant Human Fumarylacetoacetase is produced by our Mammalian expression system and the target gene encoding Ser2-Ser419 is expressed with a 6His tag at the C-terminus.

Pureté: > 95 % as determined by reducing SDS-PAGE.

niveau d'endotoxine: < 1.0 EU per μg as determined by the LAL method.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.

Stock: 4 °C,-20 °C,-80 °C

Stockage commentaire: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Détail du antigène

Antigène: FAH (Fumarylacetoacetate Hydrolase (Fumarylacetoacetase) (FAH))

Autre désignation: Fumarylacetoacetase/FAH (FAH Produits)

Synonymes: CG14993 Protein, Dmel\\CG14993 Protein, dfaa Protein, l(3)64Al Protein, l(3)SH11 Protein, PSPTO3550 Protein, fb59b12 Protein, wu:fb59b12 Protein, zgc:55316 Protein, FAA Protein, Fumarylacetoacetase Protein, FumarylAcetoacetate Hydrolase Protein, fumarylacetoacetase Protein, fumarylacetoacetate hydrolase Protein, fumarylacetoacetate hydrolase (fumarylacetoacetase) Protein, fumarylacetoacetate hydrolase (fumarylacetoacetase) L homeolog Protein, Faa Protein, fah-1 Protein, fahA Protein, hmgB Protein, Ndas_1870 Protein, Lbys_3503 Protein, Riean_0663 Protein, Ftrac_0820 Protein, Celal_3675 Protein, Celly_2655 Protein, Weevi_0208 Protein, Fluta_2435 Protein, Halhy_2019 Protein, Lacal_2931 Protein, FsymDg_1892 Protein, Fah Protein, fah Protein, fah.L Protein, FAH Protein

Sujet:

Background: Fumarylacetoacetase belongs to the FAH family. Fumarylacetoacetase is primary expressed in liver and kidney. It exists as a homodimer and catalyzes the hydrolysis of 4-fumarylacetoacetate into fumarate and acetoacetate. Defects in Fumarylacetoacetase cause tyrosinemia type 1, which is congenital metabolism defect characterized by elevated levels of tyrosine in the blood and urine, and hepatorenal manifestations. Typical features include renal tubular injury, self-mutilation, hepatic necrosis, episodic weakness, and seizures.

Synonym: Fumarylacetoacetase, FAA, Beta-Diketonase, Fumarylacetoacetate Hydrolase, FAH

Poids moléculaire: 47.4 kDa

UniProt: P16930