GSTM2 Protein (GST tag,His tag)

N° du produit ABIN7317428

Détail du produit

Antigène: GSTM2 (Glutathione S-Transferase mu 2 (Muscle) (GSTM2))

Type de proteíne: Recombinant

Origine: Humain

Source: Escherichia coli (E. coli)

Purification/Conjugué: Cette GSTM2 protéine est marqué à la GST tag,His tag.

Fonction: Recombinant Human GSTM2/GST4 Protein (His Tag)

Séquence: Met 1-Lys 218

Attributs du produit: A DNA sequence encoding the native human GSTM2 (P28161) (Met 1-Lys 218) was expressed, with a polyhistide tag at the N-terminus.

Pureté: > 97 % as determined by reducing SDS-PAGE.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from sterile 50 mM Tris, 150 mM NaCl, 10 mM CaCl2, 0.05 % Brig-35, pH 7.5

Stock: 4 °C,-20 °C,-80 °C

Stockage commentaire: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Détail du antigène

Antigène: GSTM2 (Glutathione S-Transferase mu 2 (Muscle) (GSTM2))

Autre désignation: GSTM2/GST4 (GSTM2 Produits)

Synonymes: GSTA4 Protein, GST4 Protein, GSTM Protein, GSTM2-2 Protein, GTHMUS Protein, Gstb-2 Protein, Gstb2 Protein, GSTIV Protein, glutathione S-transferase mu 2 Protein, glutathione S-transferase mu 2 (muscle) Protein, glutathione S-transferase Mu 2 Protein, glutathione S-transferase, mu 2 Protein, glutathione S-transferase 2 Protein, Glutathione S-transferase 4 Protein, Gstm2 Protein, GSTM2 Protein, LOC100732167 Protein, gst2 Protein, gst-4 Protein

Sujet:

Background: Glutathione S-transferase Mu 2, also known as GST class-mu 2, GSTM2-2 and GSTM2, is a cytoplasm protein which belongs to the GST superfamily and Mu family. GSTM2 / GST4 contains one GST C-terminal domain and one GST N-terminal domain. The glutathione S-transferases (GSTs) are a multigene family of enzymes largely involved in the detoxification of chemicals. Eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. Butyrate, an important luminal component produced from fermentation of dietary fibers, is an efficient inducer of GSTs and especially of GSTM2. Butyrate may act chemoprotectively by increasing detoxification capabilities in the colon mucosa.

Synonym: GST4;GSTM;GSTM2-2;GTHMUS

Poids moléculaire: 27.2 kDa

UniProt: P28161

Pathways: Negative Regulation of Transporter Activity