GAPDH Protein (His tag)

N° du produit ABIN7319940

Détail du produit

Antigène: GAPDH (Glyceraldehyde-3-Phosphate Dehydrogenase (GAPDH))

Type de proteíne: Recombinant

Activité biologique: Active

Origine: Humain

Source: Escherichia coli (E. coli)

Purification/Conjugué: Cette GAPDH protéine est marqué à la His tag.

Fonction: Recombinant Human GAPDH protein (His Tag)

Séquence: 1M-333E

Attributs du produit: A DNA sequence encoding the Human GAPDH (P04406) (1M-333E) was expressed with a polyhistidine tag at the N-terminus.

Pureté: >90 % as determined by reducing SDS-PAGE.

Biological Activity Comment: Immunogen(E-AB-40337)

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from sterile PBS, pH 7.4

Stock: 4 °C,-20 °C,-80 °C

Stockage commentaire: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Détail du antigène

Antigène: GAPDH (Glyceraldehyde-3-Phosphate Dehydrogenase (GAPDH))

Autre désignation: GAPDH (GAPDH Produits)

Synonymes: G3PD Protein, GAPD Protein, Gapd Protein, BEST:GH12586 Protein, CG12055 Protein, Dmel\\CG12055 Protein, GA3PDH Protein, GADPH Protein, GAP Protein, GAPDH Protein, GAPDH I Protein, GAPDH-1 Protein, GAPDH1 Protein, GAPDHI Protein, Gapdh Protein, Gapdh-1 Protein, Gapdh43E Protein, gadph Protein, gapdh Protein, gapdh-1 Protein, gh12586 Protein, cb609 Protein, gapd Protein, mg:bb02e05 Protein, wu:fb33a10 Protein, wu:ft80f05 Protein, KNC-NDS6 Protein, g3pd Protein, G3PDH Protein, glyceraldehyde-3-phosphate dehydrogenase Protein, Glyceraldehyde 3 phosphate dehydrogenase 1 Protein, glyceraldehyde-3-phosphate dehydrogenase S homeolog Protein, glyceraldehyde-3-phosphate dehydrogenase, type I Protein, olfactory receptor 8K3 Protein, GAPDH Protein, Gapdh Protein, Gapdh1 Protein, gapdh Protein, gapdh.S Protein, gapDH Protein, LOC100404960 Protein, LOC614985 Protein

Sujet:

Background: Has both glyceraldehyde-3-phosphate dehydrogenase and nitrosylase activities, thereby playing a role in glycolysis and nuclear functions, respectively. Participates in nuclear events including transcription, RNA transport, DNA replication and apoptosis. Nuclear functions are probably due to the nitrosylase activity that mediates cysteine S-nitrosylation of nuclear target proteins such as SIRT1, HDAC2 and PRKDC. Modulates the organization and assembly of the cytoskeleton. Facilitates the CHP1-dependent microtubule and membrane associations through its ability to stimulate the binding of CHP1 to microtubules (By similarity). Glyceraldehyde-3-phosphate dehydrogenase is a key enzyme in glycolysis that catalyzes the first step of the pathway by converting D-glyceraldehyde 3-phosphate (G3P) into 3-phospho-D-glyceroyl phosphate. Component of the GAIT (gamma interferon-activated inhibitor of translation) complex which mediates interferon-gamma-induced transcript-selective translation inhibition in inflammation processes. Upon interferon-gamma treatment assembles into the GAIT complex which binds to stem loop-containing GAIT elements in the 3'-UTR of diverse inflammatory mRNAs (such as ceruplasmin) and suppresses their translation.

Synonym: Aging associated gene 9 protein,Epididymis secretory sperm binding protein Li 162eP,G3P,G3PD,G3PDH,GAPD,GAPDH,Glyceraldehyde 3 phosphate dehydrogenase,Glyceraldehyde-3-phosphate dehydrogenase,HEL S 162eP,Peptidyl-cysteine S-nitrosylase GAPDH

Poids moléculaire: 37.1kDa

UniProt: P04406