IL-11 Protein (AA 22-199) (Fc Tag)

N° du produit ABIN7320821

Cette protéine Recombinant IL-11 est produite dans HEK-293 Cells.

Aperçu rapide pour IL-11 Protein (AA 22-199) (Fc Tag) (ABIN7320821)

Antigène: IL-11 (IL11) (Interleukin 11 (IL11))

Type de proteíne: Recombinant

Origine: Souris

Source: HEK-293 Cells

Pureté: > 95 % as determined by reducing SDS-PAGE.

Détail du produit

Attributs du protein: AA 22-199

Purification/Conjugué: Cette IL-11 protéine est marqué à la Fc Tag.

Fonction: Recombinant Mouse Interleukin-11/IL-11 Protein (Fc Tag)

Séquence: Pro22-Leu199

Attributs du produit: Recombinant Mouse Interleukin-11 is produced by our Mammalian expression system and the target gene encoding Pro22-Leu199 is expressed with a Fc tag at the C-terminus.

Stérilité: 0.2 μm filtered

niveau d'endotoxine: < 1.0 EU per μg of the protein as determined by the LAL method.

Biological Activity Comment: Not validated for activity

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: Lyophilized from a 0.2 μm filtered solution of 10 mM HAc-NaAc, 150 mM NaCl, 0.004 % Tween 80, 5 % Mannitol, pH 4.0.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween 80 are added as protectants before lyophilization.

Stock: 4 °C,-20 °C,-80 °C

Stockage commentaire: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Date de péremption: 12 months

Détail du antigène

Antigène: IL-11 (IL11) (Interleukin 11 (IL11))

Autre désignation: Interleukin-11/IL-11

Sujet: Interleukin,IL-11,Interleukin-11,Zcyto1,Zcyto10,Il11,AGIF,interleukin 11,Interleukin-11(IL-11) is a secreted protein and belongs to the IL-6 superfamily. IL-11 has been demonstrated to improve platelet recovery after chemotherapy-induced thrombocytopenia, induceacute phase proteins, modulate antigen-antibody responses, participate in the regulation of bone cellproliferation and differentiation and could be use as a therapeutic for osteoporosis. IL-11 stimulates the growth of certain lymphocytes and, in the murine model, stimulates an increase in the cortical thickness and strength of long bones. In addition to having lymphopoietic/hematopoietic and osteotrophic properties, it has functions in many other tissues, including the brain, gut, testis and bone.

Poids moléculaire:

Calculated MW: 46.3 kDa

Observed MW: 50-60 kDa

UniProt: P47873

Pathways: Signalistation JAK/STAT, Negative Regulation of Hormone Secretion