IL20RA Protein (His tag)

N° du produit ABIN7318609

Détail du produit

Antigène: IL20RA (Interleukin 20 Receptor alpha (IL20RA))

Type de proteíne: Recombinant

Activité biologique: Active

Origine: Humain

Source: Human Cells

Purification/Conjugué: Cette IL20RA protéine est marqué à la His tag.

Fonction: Recombinant Human IL-20RA/IL-20R1 Protein (His Tag)(Active)

Séquence: Val30-Lys250

Attributs du produit: Recombinant Human Interleukin-20 Receptor Subunit alpha is produced by our Mammalian expression system and the target gene encoding Val30-Lys250 is expressed with a 6His tag at the C-terminus.

Pureté: > 95 % as determined by reducing SDS-PAGE.

niveau d'endotoxine: < 1.0 EU per μg as determined by the LAL method.

Biological Activity Comment: Immobilized Human IL-20(Cat: PKSH032630) at 2μg/ml(100 μl/well) can bind Human IL-20RA-His. The ED50 of Human IL-20RA-His is 3.5 ug/ml .

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.4.

Stock: 4 °C,-20 °C,-80 °C

Stockage commentaire: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Détail du antigène

Antigène: IL20RA (Interleukin 20 Receptor alpha (IL20RA))

Autre désignation: IL-20RA/IL-20R1 (IL20RA Produits)

Synonymes: CRF2-8 Protein, IL-20R-alpha Protein, IL-20R1 Protein, IL-20RA Protein, E230031K19 Protein, interleukin 20 receptor subunit alpha Protein, interleukin 20 receptor, alpha Protein, IL20RA Protein, Il20ra Protein

Sujet:

Background: Interleukin-20 Receptor Subunit α (IL20RA) is a single-pass type I membrane protein that is a member of the type II cytokine receptor family. IL20RA is synthetized a 553 amino acid glycoprotein precursor containing a 29 amino acid signal peptide, a 221 amino acid extracellular domain with two fibronectin type-III domains, a 24 amino acid transmembrane region, and a 279 amino acid intracellular domain. IL20RA is widely expressed with highest levels found in skin and testis and high levels in brain. IL20RA forms a heterodimer with IL20RB, and the complex serves as a receptor for IL19, IL20 and IL24. IL20RA also forms a heterodimer with the unique and specific receptor IL10RB and functions as the receptor for IL26.

Synonym: Interleukin-20 Receptor Subunit Alpha, IL-20 Receptor Subunit Alpha, IL-20R-Alpha, IL-20RA, Cytokine Receptor Class-II Member 8, Cytokine Receptor Family 2 Member 8, CRF2-8, IL-20R1, ZcytoR7, IL20RA

Poids moléculaire: 26.3 kDa

UniProt: Q9UHF4