IZUMO1 Protein (His tag)

N° du produit ABIN7317232

Détail du produit

Antigène: IZUMO1 (Izumo Sperm-Egg Fusion 1 (IZUMO1))

Type de proteíne: Recombinant

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette IZUMO1 protéine est marqué à la His tag.

Fonction: Recombinant Human IZUMO1 Protein (His Tag)

Séquence: Met 1-Arg292

Attributs du produit: A DNA sequence encoding the human IZUMO1 (AAH34769.1) (Met1-Arg292) was expressed with a polyhistidine tag at the C-terminus.

Pureté: > 95 % as determined by reducing SDS-PAGE.

niveau d'endotoxine: < 1.0 EU per μg as determined by the LAL method.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from sterile PBS, pH 7.4

Stock: 4 °C,-20 °C,-80 °C

Stockage commentaire: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Détail du antigène

Antigène: IZUMO1 (Izumo Sperm-Egg Fusion 1 (IZUMO1))

Autre désignation: IZUMO1 (IZUMO1 Produits)

Synonymes: IZUMO Protein, 1700058F15Rik Protein, Izumo Protein, izumo sperm-egg fusion 1 Protein, Ras interacting protein 1 Protein, IZUMO1 Protein, RASIP1 Protein, Izumo1 Protein

Sujet:

Background: Izumo is a sperm membrane protein which plays a key role in the fusion in the mouse. It has an Immunoglobulin (Ig) domain and an N-terminal domain for which neither the functions nor homologous sequences are known. Up to now, there four members has an N-terminal domain with significant homology to the N-terminal domain of Izumo. We call this domain Izumo domain. The four proteins are Izumo 1, 2, 3, and 4. Izumo domain possesses the ability to form dimers, whereas the transmembrane domain or the cytoplasmic domain or both of Izumo 1 are required for the formation of multimers of higher order. Izumo 1-3 are transmembrane proteins expressed specifically in the testis, and Izumo 4 is a soluble protein expressed in the testis and in other tissues. Izumo 1, 3, and 4 formed protein complexes on sperm, Izumo 1 forming several larger complexes and Izumo 3 and 4 forming a single larger complex. Izumo1 is essential for sperm-egg plasma membrane binding and fusion.

Synonym: IZUMO

Poids moléculaire: 32.1 kDa