JTB Protein (Fc Tag)

N° du produit ABIN7317243

Détail du produit

Antigène: JTB (Jumping Translocation Breakpoint (JTB))

Type de proteíne: Recombinant

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette JTB protéine est marqué à la Fc Tag.

Fonction: Recombinant Human Jumping Translocation Breakpoint/JTB Protein (Fc Tag)

Séquence: Met 1-Leu105

Attributs du produit: A DNA sequence encoding the human JTB (O76095-1) (Met1-Leu105) was fused with Fc region of mouse IgG at the C-terminus.

Pureté: > 85 % as determined by reducing SDS-PAGE.

niveau d'endotoxine: < 1.0 EU per μg as determined by the LAL method.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from sterile PBS, pH 7.4

Stock: 4 °C,-20 °C,-80 °C

Stockage commentaire: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Détail du antigène

Antigène: JTB (Jumping Translocation Breakpoint (JTB))

Autre désignation: Jumping Translocation Breakpoint/JTB (JTB Produits)

Synonymes: HJTB Protein, HSPC222 Protein, PAR Protein, hJT Protein, Gm622 Protein, JTB Protein, jumping translocation breakpoint Protein, JTB Protein, Jtb Protein

Sujet:

Background: Jumping translocation breakpoint, also known as JTB, is a member of the JTB family. Jumping translocation (JT) is an unbalanced translocation that comprises amplified chromosomalsegments jumping to various telomeres. JTB is expressed in all normal human tissues studied but overexpressed or underexpressed in many of their malignant counterparts. It is required for normal cytokinesis during mitosis. JTB plays a role in the regulation of cell proliferation. It may be a component of the chromosomal passenger complex (CPC), a complex that acts as a key regulator of mitosis. The CPC complex has essential functions at the centromere in ensuring correct chromosome alignment and segregation and is required for chromatin-induced microtubule stabilization and spindle assembly.

Synonym: hJT,HJTB,HSPC222,JTB,PAR

Poids moléculaire: 34.7 kDa