JAM2 Protein (His tag)

N° du produit ABIN7318693

Détail du produit

Antigène: JAM2 (Junctional Adhesion Molecule 2 (JAM2))

Type de proteíne: Recombinant

Origine: Humain

Source: Human Cells

Purification/Conjugué: Cette JAM2 protéine est marqué à la His tag.

Fonction: Recombinant Human JAM-B/CD322 Protein (His Tag)

Séquence: Phe29-Asn236

Attributs du produit: Recombinant Human Junctional Adhesion Molecule B is produced by our Mammalian expression system and the target gene encoding Phe29-Asn236 is expressed with a 6His tag at the C-terminus.

Pureté: > 95 % as determined by reducing SDS-PAGE.

niveau d'endotoxine: < 1.0 EU per μg as determined by the LAL method.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.2.

Stock: 4 °C,-20 °C,-80 °C

Stockage commentaire: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Détail du antigène

Antigène: JAM2 (Junctional Adhesion Molecule 2 (JAM2))

Autre désignation: JAM-B/CD322 (JAM2 Produits)

Synonymes: JAM2 Protein, cd322 Protein, jam-b Protein, jamb Protein, pro245 Protein, ve-jam Protein, vejam Protein, jam2 Protein, sb:cb1002 Protein, im:7155552 Protein, sc:d0813 Protein, si:ch211-160b11.5 Protein, LOC100227766 Protein, 1110002N23Rik Protein, 2410030G21Rik Protein, 2410167M24Rik Protein, JAM-2 Protein, JAM-B Protein, Jcam2 Protein, VE-JAM Protein, C21orf43 Protein, CD322 Protein, JAMB Protein, PRO245 Protein, VEJAM Protein, junctional adhesion molecule 2 Protein, junctional adhesion molecule 2a Protein, junctional adhesion molecule 2b Protein, junction adhesion molecule 2 Protein, JAM2 Protein, jam2 Protein, jam2a Protein, jam2b Protein, Jam2 Protein

Sujet:

Background: Junctional Adhesion Molecule B (JAM-B) is a single-pass type I membrane protein that belongs to the juctional adhesion molecules family. JAM-B includes a signal sequence (aa 1-28), an extracellular region (aa 29-238) with one Ig-like C2-type domain and one Ig-like V-type domain, a transmembrane segment (aa 239-259), and a cytoplasmic domain (aa 260 - 298). JAMB is localized to the tight junctions between endothelial cells or epithelial cells. JAM-B is prominently expressed in the heart, placenta, lung, foreskin and lymph node. It is also present on the endothelia of other vessels. JAM-B acts as an adhesive ligand for interacting with a variety of immune cell types and may play a role in lymphocyte homing to secondary lymphoid organs.

Synonym: Junctional Adhesion Molecule B, JAM-B, Junctional Adhesion Molecule 2, JAM-2, Vascular Endothelial Junction-Associated Molecule, VE-JAM, CD322, JAM2, C21orf43, VEJAM

Poids moléculaire: 24.3 kDa

UniProt: P57087