LEFTY2 Protein (His tag)

N° du produit ABIN7318717

Détail du produit

Antigène: LEFTY2 (Left-Right Determination Factor 2 (LEFTY2))

Type de proteíne: Recombinant

Origine: Humain

Source: Human Cells

Purification/Conjugué: Cette LEFTY2 protéine est marqué à la His tag.

Fonction: Recombinant Human LEFTY2 Protein (His Tag)

Séquence: Phe78-Pro366

Attributs du produit: Recombinant Human Left-right Determination Factor 2 is produced by our Mammalian expression system and the target gene encoding Phe78-Pro366 is expressed with a 6His tag at the N-terminus.

Pureté: > 90 % as determined by reducing SDS-PAGE.

niveau d'endotoxine: < 1.0 EU per μg as determined by the LAL method.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.

Stock: 4 °C,-20 °C,-80 °C

Stockage commentaire: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Détail du antigène

Antigène: LEFTY2 (Left-Right Determination Factor 2 (LEFTY2))

Autre désignation: LEFTY2 (LEFTY2 Produits)

Synonymes: EBAF Protein, LEFTA Protein, LEFTYA Protein, TGFB4 Protein, AI450052 Protein, Ebaf Protein, Leftb Protein, Stra3 Protein, Tgfb4 Protein, lefty Protein, lefty-1 Protein, atv2 Protein, cb720 Protein, fe38b03 Protein, wu:fe38b03 Protein, 6030463A22Rik Protein, AV214969 Protein, Lefta Protein, Ebaf2 Protein, left-right determination factor 2 Protein, left right determination factor 1 Protein, lefty2 Protein, Left-right determination factor 2 Protein, left-right determination factor 2-like Protein, LEFTY2 Protein, Lefty1 Protein, lft2 Protein, Lefty2 Protein, LOC699676 Protein, LOC100232580 Protein

Sujet:

Background: Left-right determination factor 2(LEFTY2) is a secreted protein which belongs to the TGF-beta family. Lefty was first identified in a screen for undifferentiated cell-specific cDNAs from the P19 mouse embryonal carcinoma cells. Its mRNA expression on the left side of the developing embryo earned the name ""Lefty"". The human orthologue was initially identified as Ebaf, Endometrial bleeding associated factor. Lefty contains the six cysteine residues that are conserved among TGF-β related proteins and that are necessary to form the cysteineknot structure. Its function in patterning left-right asymmetry of the developing organ systems such as the heart and lung is consistent in all vertebrate species examined. Lefty acts as an antagonist to Nodal signaling, potentially by competing for binding to a common receptor. It may play a role in endometrial bleeding.

Synonym: Left-right determination factor 2, Endometrial bleeding-associated factor, Left-right determination factor A, Protein lefty-2, Protein lefty-A, Transforming growth factor beta-4, TGF-beta-4, LEFTY2, EBAF, LEFTA, LEFTYA, TGFB4

Poids moléculaire: 39.1 kDa

UniProt: O00292