LRP10 Protein (Fc Tag)

N° du produit ABIN7317281

Détail du produit

Antigène: LRP10 (Low Density Lipoprotein Receptor Related Protein 10 (LRP10))

Type de proteíne: Recombinant

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette LRP10 protéine est marqué à la Fc Tag.

Fonction: Recombinant Human LRP10 Protein (Fc Tag)

Séquence: Met 1-Lys 440

Attributs du produit: A DNA sequence encoding the human LRP10 (Q7Z4F1-1) extracellular domain (Met 1-Lys 440) was fused with the Fc region of human IgG1 at the C-terminus.

Pureté: > 88 % as determined by reducing SDS-PAGE.

niveau d'endotoxine: < 1.0 EU per μg of the protein as determined by the LAL method.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from sterile PBS, pH 7.4

Stock: 4 °C,-20 °C,-80 °C

Stockage commentaire: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Détail du antigène

Antigène: LRP10 (Low Density Lipoprotein Receptor Related Protein 10 (LRP10))

Autre désignation: LRP10 (LRP10 Produits)

Synonymes: LRP9 Protein, MST087 Protein, Lrp9 Protein, LDL receptor related protein 10 Protein, low-density lipoprotein receptor-related protein 10 Protein, LRP10 Protein, Lrp10 Protein

Sujet:

Background: Various members of the low-density lipoprotein receptor (LDLR) family have been reported to play a role in APP trafficking and processing and are important risk factors in AD.LDLR-related protein 1 (LRP1) shuttles between the trans-Golgi Network (TGN), plasma membrane (PM), and endosomes.LRP1 is a functional APP receptor involved in APP trafficking and processing. LRP1 interacts directly with the ectodomain of APP and colocalizes with APP at the TGN. LRP1 is a novel APP sorting receptor that protects APP from amyloidogenic processing, suggesting that a decrease in LRP1 function may contribute to the pathogenesis of Alzheimer's disease.

Synonym: LRP9,MST087,MSTP087

Poids moléculaire: 73 kDa