LSM1 Protein (His tag)

N° du produit ABIN7319137

Détail du produit

Antigène: LSM1 (LSM1 Homolog, U6 Small Nuclear RNA Associated (LSM1))

Type de proteíne: Recombinant

Origine: Humain

Source: Escherichia coli (E. coli)

Purification/Conjugué: Cette LSM1 protéine est marqué à la His tag.

Fonction: Recombinant Human LSM1 Protein (His Tag)

Séquence: Met 1-Tyr133

Attributs du produit: Recombinant Human U6 snRNA-Associated Sm-Like Protein LSm1 is produced by our E.coli expression system and the target gene encoding Met1-Tyr133 is expressed with a 6His tag at the C-terminus.

Pureté: > 90 % as determined by reducing SDS-PAGE.

niveau d'endotoxine: < 1.0 EU per μg as determined by the LAL method.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.2.

Stock: 4 °C,-20 °C,-80 °C

Stockage commentaire: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Détail du antigène

Antigène: LSM1 (LSM1 Homolog, U6 Small Nuclear RNA Associated (LSM1))

Autre désignation: LSM1 (LSM1 Produits)

Synonymes: lsm1 Protein, NV45 Protein, CASM Protein, YJL124C Protein, 2810025O06Rik Protein, zgc:101136 Protein, LSM1 homolog, mRNA degradation associated Protein, LSM1 homolog, U6 small nuclear RNA associated Protein, LSM1 homolog, mRNA degradation associated L homeolog Protein, LSM1, U6 small nuclear RNA associated Protein, lsm1 Protein, Lsm1 Protein, lsm1.L Protein, LSM1 Protein

Sujet:

Background: U6 snRNA-Associated Sm-Like Protein LSm1 (LSM1) belongs to the snRNP Sm proteins family. The Sm-like proteins are thought to form a stable heteromer present in tri-snRNP particles, which plays an important role in pre-mRNA splicing. LSM1 binds specifically to the 3-terminal U-tract of U6snRNA. LSM1 can interact with SLBP when histone mRNA is being rapidly degraded during the S phase. In addition, LSM1 is associated with cellular transformation and the progression of several malignancies including mesothelioma, lung cancer and breast cancer.

Synonym: U6 snRNA-Associated Sm-Like Protein LSm1, Cancer-Associated Sm-Like, Small Nuclear Ribonuclear CaSm, LSM1, CASM

Poids moléculaire: 16.2 kDa

UniProt: O15116