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Medium-Chain Specific Acyl-CoA Dehydrogenase, Mitochondrial protein (His tag)

Origine: Humain Hôte: Escherichia coli (E. coli) Recombinant > 95 % as determined by reducing SDS-PAGE.
N° du produit ABIN7318123
  • Antigène
    Medium-Chain Specific Acyl-CoA Dehydrogenase, Mitochondrial
    Type de proteíne
    Recombinant
    Origine
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Humain
    Source
    • 5
    • 2
    • 2
    • 1
    • 1
    Escherichia coli (E. coli)
    Purification/Conjugué
    His tag
    Fonction
    Recombinant Human ACADM/MCAD Protein (His Tag)
    Séquence
    Lys26-Asn421
    Attributs du produit
    Recombinant Human Medium-Chain Specific Acyl-CoA Dehydrogenase, Mitochondrial is produced by our E.coli expression system and the target gene encoding Lys26-Asn421 is expressed with a 6His tag at the N-terminus.
    Pureté
    > 95 % as determined by reducing SDS-PAGE.
    niveau d'endotoxine
    < 1.0 EU per μg as determined by the LAL method.
  • Restrictions
    For Research Use only
  • Format
    Frozen, Liquid
    Buffer
    Supplied as a 0.2 μm filtered solution of 20 mM Tris, 0.1M NaCl, 20 % Glycerol, pH 8.5.
    Stock
    -20 °C
    Stockage commentaire
    Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
  • Antigène
    Medium-Chain Specific Acyl-CoA Dehydrogenase, Mitochondrial
    Autre désignation
    ACADM/MCAD
    Synonymes
    ACAD1 Protein, MCAD Protein, MCADH Protein, AU018656 Protein, acyl-CoA dehydrogenase medium chain Protein, acyl-Coenzyme A dehydrogenase, medium chain Protein, acyl-CoA dehydrogenase, C-4 to C-12 straight chain Protein, ACADM Protein, Acadm Protein
    Sujet

    Background: Medium-Chain Specific Acyl-CoA Dehydrogenase (ACADM) is a mitochondrial fatty acid beta-oxidation that belongs to the acyl-CoA dehydrogenase family. ACADM is a homotetramer enzyme that catalyzes the initial step of the mitochondrial fatty acid beta-oxidation pathway. ACADM is specific for acyl chain lengths of 4 to 16. It is essential for converting these particular fatty acids to energy, especially during fasting periods. Defects in ACADM cause medium-chain acyl-CoA dehydrogenase deficiency, a disease characterized by hepatic dysfunction, fasting hypoglycemia, and encephalopathy, which can result in infantile death.

    Synonym: Medium-Chain Specific Acyl-CoA Dehydrogenase Mitochondrial, MCAD, ACADM

    Poids moléculaire
    45.9 kDa
    UniProt
    P11310
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