METTL1 Protein (His tag)

N° du produit ABIN7317547

Détail du produit

Antigène: METTL1 (Methyltransferase Like 1 (METTL1))

Type de proteíne: Recombinant

Origine: Humain

Source: Escherichia coli (E. coli)

Purification/Conjugué: Cette METTL1 protéine est marqué à la His tag.

Fonction: Recombinant Human METTL1 Protein (His Tag)

Séquence: Asp 32-Gln 265

Attributs du produit: A DNA sequence encoding the human METTL1 (NP_005362.3) (Asp 32-Gln 265) was expressed, with a polyhistide tag at the N-terminus.

Pureté: > 95 % as determined by reducing SDS-PAGE.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from sterile 50 mM Tris, 0.5M NaCl, 20 % glycerol, pH 8.0

Stock: 4 °C,-20 °C,-80 °C

Stockage commentaire: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Détail du antigène

Antigène: METTL1 (Methyltransferase Like 1 (METTL1))

Autre désignation: METTL1 (METTL1 Produits)

Synonymes: Dmel\\CG4045 Protein, EG:22E5.4 Protein, C12orf1 Protein, TRM8 Protein, TRMT8 Protein, YDL201w Protein, 2810012D02Rik Protein, CG4045 gene product from transcript CG4045-RA Protein, methyltransferase like 1 Protein, methyltransferase like 1 L homeolog Protein, tRNA (guanine46-N7)-methyltransferase Protein, tRNA (guanine-N(1)-)-methyltransferase Protein, tRNA (guanine-N7-)-methyltransferase Protein, CG4045 Protein, METTL1 Protein, Mettl1 Protein, mettl1.L Protein, CAALFM_C404810CA Protein, LOC100280508 Protein, LOC732983 Protein

Sujet:

Background: tRNA (guanine-N(7)-)-methyltransferase, also known as Methyltransferase-like protein 1, tRNA (m7G46)-methyltransferase and METTL1, is a nucleus protein which belongs to the methyltransferase superfamily and TrmB family. METTL1 gene, has been identified by its sequence similarity to the yeast ORF YDL201w. The human cDNA and the genomic structure of METTL1 have been analyzed. The transcript contains 1292 nucleotides and codes for a protein of 276 amino acids. The METTL1 gene product shows high sequence similarities to putative proteins from mouse, Drosophila melanogaster, Arabidopsis thaliana, Caenorhabditis elegans, and yeast (39.8% identity between all six species). Computer analyses of the deduced protein sequence reveal two highly conserved amino acid motifs, one of which is typical for methyltransferases. Both motifs are also present in hypothetical proteins from eubacteria. Disruption of the homologous yeast ORF YDL201w shows that the gene is at least not essential for vegetative growth in Saccharomyces cerevisiae.

Synonym: C12orf1;TRM8;TRMT8;YDL201w

Poids moléculaire: 28 kDa

NCBI Accession: NP_005362